Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.61 |
| ▸ | CCR8 | P51685 | 1/20 | 0.54 |
| ▸ | TACR1 | P25103 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13145572 | 0.95 | KCNH2 (0.65) | KCNH2CCR8TACR1ALDH1A1GAA | |
| SCHEMBL14514811 | 0.87 | KCNH2 (0.59) | KCNH2CCR8SLC2A1 | |
| SCHEMBL3692137 | 0.82 | MEN1 (0.49) | MEN1KMT2A | |
| SCHEMBL3690915 | 0.78 | KCNH2 (0.74) | KCNH2SLC2A1 | |
| SCHEMBL3690789 | 0.78 | KCNH2 (0.48) | KCNH2CCR8TACR1 | |
| SCHEMBL14514812 | 0.76 | ALDH1A1 (0.47) | KCNH2TACR1ALDH1A1GAAMAPT | |
| SCHEMBL7466144 | 0.75 | CCR8 (0.53) | KCNH2CCR8ALDH1A1GAAKDM4E | |
| SCHEMBL7455480 | 0.75 | CCR8 (0.53) | KCNH2CCR8ALDH1A1KDM4EMAPT | |
| SCHEMBL7560175 | 0.75 | CCR8 (0.53) | KCNH2CCR8ALDH1A1GAAKDM4E | |
| SCHEMBL3690391 | 0.75 | KCNH2 (0.49) | KCNH2TACR1SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2239260-A1 | Novel compounds with antibacterial activity | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2010-10-13 | — | — | EP | disclosed |
| EP-2239260-A1 | Novel compounds with antibacterial activity | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2010-10-13 | — | — | EP | disclosed |
| CN-101817815-A | Compounds with antibacterial activity | MORPHOCHEM AG KOMB CHEMIE | 2010-09-01 | — | — | CN | disclosed |
| CN-100569769-C | Compounds with fungicidal activity | MORPHOCHEM AG KOMB CHEMIE (DE) | 2009-12-16 | — | — | CN | disclosed |
| US-7223776-B2 | Compounds with anti-bacterial activity | MORPHOCHEM AG (DE) | 2007-05-29 | — | — | US | disclosed |
| US-7223776-B2 | Compounds with anti-bacterial activity | MORPHOCHEM AG (DE) | 2007-05-29 | — | — | US | disclosed |
| US-7223776-B2 | Compounds with anti-bacterial activity | MORPHOCHEM AG (DE) | 2007-05-29 | — | — | US | disclosed |
| US-20060040949-A1 | Novel compounds with antibacterial activity | MORPHOCHEM AG | 2006-02-23 | — | — | US | disclosed |
| CN-1703412-A | Novel compounds with fungicidal activity | MORPHOCHEM AG KOMB CHEMIE (DE) | 2005-11-30 | — | — | CN | disclosed |
| EP-1551829-A2 | NOVEL COMPOUNDS WITH ANTIBACTERIAL ACTIVITY | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2005-07-13 | — | — | EP | disclosed |
| WO-2004035569-A2 | NOVEL COMPOUNDS WITH ANTIBACTERIAL ACTIVITY | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2004-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040949-A1 | Novel compounds with antibacterial activity | MRPL21, Q6ZSR9, MRPL19 | KCNH2 2411/4885CCR8 3798/4885TACR1 3827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.