SCHEMBL369224

SCHEMBL369224

CCOC(=O)c1cn[nH]c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 2/20 0.51
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
ALDH1A1 P00352 2/20 0.49
CA12 O43570 3/20 0.48
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
CA7 P43166 3/20 0.48
CA9 Q16790 3/20 0.48
CA14 Q9ULX7 3/20 0.48
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
CYP1A2 P05177 2/20 0.47
LMNA P02545 1/20 0.47
CYP3A4 P08684 1/20 0.47
MAOA P21397 1/20 0.47
JMJD6 Q6NYC1 1/20 0.43
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL29259257 0.98 NAMPT (0.50) NAMPTCYP2C9CYP2C19KMT2AMEN1
Trifluoroacetic Acid SCHEMBL30271698 0.89 CYP2C9 (0.45) NAMPTCYP2C9CYP2C19KMT2AMEN1
SCHEMBL19100018 0.85 LMNA (0.53) NAMPTCYP2C9CYP2C19KMT2AMEN1
SCHEMBL28125901 0.82 L3MBTL1 (0.55) CYP2C9CYP2C19ESR1CYP1A2LMNA
SCHEMBL5246921 0.81 ALDH1A1 (0.40) NAMPTCYP2C9CYP2C19KMT2AMEN1
SCHEMBL28308037 0.81 LMNA (0.55) CYP2C9CYP2C19ALDH1A1ESR1CYP1A2
SCHEMBL16481109 0.81 ALDH1A1 (0.37) NAMPTCYP2C9CYP2C19KMT2AMEN1
SCHEMBL28100323 0.81 ALDH1A1 (0.41) NAMPTCYP2C9CYP2C19KMT2AMEN1
SCHEMBL22694443 0.81 KDM4E (0.47) NAMPTKMT2AMEN1ALDH1A1HPGD
SCHEMBL29058357 0.80 ALDH1A1 (0.47) NAMPTALDH1A1JMJD6TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2436 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119301113-A Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors 豪夫迈·罗氏有限公司 2025-01-10 CN claimed
CN-118265452-A Fungicidal compositions 先正达农作物保护股份公司 2024-06-28 CN claimed
CN-114249785-B Preparation method of 2-adenosine N-pyrazole derivative regadenoson 常州方圆制药有限公司 2024-04-05 CN claimed
CN-116234444-A Mixtures with insecticidal activity comprising sulfur-containing heterocyclylalkoxy compounds, oxides or salts thereof 皮埃企业有限公司 2023-06-06 CN claimed
CN-115802893-A Fungicidal compositions 先正达农作物保护股份公司 2023-03-14 CN claimed
CN-115697063-A Fungicidal compositions 先正达农作物保护股份公司 2023-02-03 CN claimed
CN-112107568-B Diaryl amide compound and application thereof 北京龙嘉博创医药科技有限公司 2022-03-25 CN claimed
CN-113966171-A Fungicidal compositions 先正达农作物保护股份公司 2022-01-21 CN claimed
CN-112480006-A Synthetic preparation method of 4-pyrazole ethyl formate 南京麦瑞米生物技术有限公司 2021-03-12 CN claimed
CN-211800833-U Reation kettle is used in production of 4 pyrazole ethyl formate 南京麦瑞米生物技术有限公司 2020-10-30 CN claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
US-6106599-A Inks XEROX CORPORATION (US) 2000-08-22 US claimed
EP-0673783-B1 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORP (US) 2000-07-05 EP claimed
US-5659348-A APPLYING TO A SUBSTRATE XEROX CORPORATION (US) 1997-08-19 US claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0673783-A2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 1995-09-27 EP claimed