SCHEMBL369247

SCHEMBL369247

CC(C)[Si](C(C)C)(C(C)C)n1ccc(Br)c1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3860625 0.74 CNR1 (0.30) CNR1
SCHEMBL860388 0.74 CNR1 (0.30) CNR1
SCHEMBL18527308 0.74 CNR1 (0.30) CNR1
SCHEMBL19008983 0.74 CNR1 (0.33) CNR1
SCHEMBL14908941 0.73 CYP2A6 (0.41) CNR1
SCHEMBL1671736 0.72
SCHEMBL3580246 0.70 GRM5 (0.41)
SCHEMBL4559390 0.69 TYR (0.36) CNR1
SCHEMBL18300454 0.69 CNR1 (0.43) CNR1
SCHEMBL19650143 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4619402-A1 GPR17 MODULATORS AND USES THEREOF Myrobalan Therapeutics, Inc. (US) 2025-09-24 EP disclosed
US-20250230169-A1 Phosphoinositide 3-Kinase Inhibitors with a Zinc Binding Moiety CURIS INC (US) 2025-07-17 US disclosed
CN-119613396-A Pyrrolo-heterocyclic-3-sulfonamide compounds and their use in the preparation of inhibitors of the GPR17 receptor 迈巴制药(南京)有限公司 2025-03-14 CN disclosed
WO-2024188287-A1 BRM INHIBITOR AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 贝达药业股份有限公司 2024-09-19 WO disclosed
US-20240299385-A1 3-PYRROLYLSULFONAMIDE COMPOUNDS AS GPR17 ANTAGONISTS REWIND THERAPEUTICS NV (BE) 2024-09-12 US disclosed
WO-2024104462-A1 GPR17 MODULATORS AND USES THEREOF MYROBALAN THERAPEUTICS NANJING CO. LTD (CN) 2024-05-23 WO disclosed
EP-4347558-A1 3-PYRROLYLSULFONAMIDE COMPOUNDS AS GPR17 ANTAGONISTS ReWind Therapeutics NV (BE) 2024-04-10 EP disclosed
CN-117794898-A 3-pyrrolylsulfonamide compounds as GPR17 antagonists 瑞文德医疗公众有限公司 2024-03-29 CN disclosed
CN-116568686-A Substituted pyrrolo [2,3-b ] pyridine and pyrazolo [3,4-b ] pyridine derivatives as protein kinase inhibitors 重庆复尚源创医药技术有限公司 2023-08-08 CN disclosed
US-20230227467-A1 PHOSPHOINOSITIDE 3-KINASE INHIBITORS WITH A ZINC BINDING MOIETY CURIS INC (US) 2023-07-20 US disclosed
US-5472933-A Plant growth regulators E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-12-05 US disclosed
WO-1995022545-A1 2-HETEROARYL-5,11-DIHYDRO-6H-DIPYRIDO[3,2-b:2',3'-e][1,4]DIAZEPINES AND THEIR USE IN THE PREVENTION OR TREATMENT OF HIV INFECTION BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) 1995-08-24 WO disclosed
EP-0656359-A1 Substituted 6,11-ethano-6,11-dihydrobenzo[b]quinolizinium salts and compositionsand methods of use thereof STERLING WINTHROP INC. (US) 1995-06-07 EP disclosed
EP-0647641-A1 Substituted heterocyclylisoquinolinium salts and compositions and methods of usethereof STERLING WINTHROP INC. (US) 1995-04-12 EP disclosed
US-5356862-A Herbicidal sulfonylureas E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-10-18 US disclosed
EP-0544705-A1 DERIVATIVES OF MUPIROCIN Beecham Group p.l.c. (GB) 1993-06-09 EP disclosed
EP-0511993-A1 HERBICIDAL SULFONYLUREAS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-11-11 EP disclosed
WO-1992004319-A1 HERBICIDAL PYRROLESULFONYLUREAS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-03-19 WO disclosed
WO-1992002518-A1 DERIVATIVES OF MUPIROCIN BEECHAM GROUP PLC (GB) 1992-02-20 WO disclosed
WO-1991010668-A1 HERBICIDAL SULFONYLUREAS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-07-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250230169-A1 Phosphoinositide 3-Kinase Inhibitors with a Zinc Binding Moiety BAZ2A, BAZ2B, PI4KB CNR1 4779/4885
US-20240299385-A1 3-PYRROLYLSULFONAMIDE COMPOUNDS AS GPR17 ANTAGONISTS GPR3, GPR27, GPR65 CNR1 29/4885
US-20230227467-A1 PHOSPHOINOSITIDE 3-KINASE INHIBITORS WITH A ZINC BINDING MOIETY BAZ2A, BAZ2B, PI4KB CNR1 4779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.