SCHEMBL29453232

SCHEMBL29453232

C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MME P08473 1/20 0.58
ECE1 P42892 1/20 0.58
CTSK P43235 3/20 0.58
CASP1 P29466 8/20 0.54
CAPN1 P07384 1/20 0.52
CASP3 P42574 1/20 0.51
PSMB8 P28062 1/20 0.51
PSMB9 P28065 1/20 0.51
PSMB5 P28074 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7155003 0.99 MME (0.59) MMEECE1CTSKCASP1CAPN1
SCHEMBL14433707 0.99 MME (0.59) MMEECE1CTSKCASP1CAPN1
SCHEMBL4430771 0.99 MME (0.59) MMEECE1CTSKCASP1CAPN1
SCHEMBL10868042 0.93 CAPN1 (0.58) MMEECE1CTSKCASP1CAPN1
SCHEMBL614741 0.92 CASP3 (0.62) MMEECE1CTSKCASP1CASP3
SCHEMBL3140616 0.92 CASP3 (0.62) MMEECE1CTSKCASP1CASP3
SCHEMBL24992811 0.90 MME (0.59) MMEECE1CTSKCAPN1PSMB8
SCHEMBL20263591 0.90 MME (0.59) MMEECE1CTSKCAPN1PSMB8
SCHEMBL20677213 0.90 MME (0.59) MMEECE1CTSKCAPN1PSMB8
SCHEMBL14371944 0.90 MME (0.59) MMEECE1CTSKCAPN1PSMB8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3802850-B1 DEVICES AND SYSTEMS FOR GASTROINTESTINAL MICROBIOME DETECTION AND MANIPULATION BT BIDCO INC (US) 2025-11-19 EP disclosed
US-20250082265-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH AN IMMUNOSUPPRESSANT BT BIDCO, INC. 2025-03-13 US disclosed
US-20250000364-A1 GASTROINTESTINAL TRACT DETECTION METHODS, DEVICES AND SYSTEMS GLAS USA LLC 2025-01-02 US disclosed
US-12150775-B2 Treatment of a disease of the gastrointestinal tract with an immunosuppressant BIORA THERAPEUTICS, INC. (US) 2024-11-26 US disclosed
CN-118873822-A Treatment of gastrointestinal disorders with TNF inhibitors 比奥拉治疗股份有限公司 2024-11-01 CN disclosed
US-20240335644-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH AN IMMUNE MODULATORY AGENT RELEASED USING AN INGESTIBLE DEVICE GLAS USA LLC 2024-10-10 US disclosed
US-12089916-B2 Gastrointestinal tract detection methods, devices and systems BIORA THERAPEUTICS, INC. (US) 2024-09-17 US disclosed
EP-4410832-A2 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A TNF INHIBITOR Biora Therapeutics, Inc. (US) 2024-08-07 EP disclosed
CN-110430801-B Treatment of gastrointestinal disorders with TNF inhibitors 比奥拉治疗股份有限公司 2024-04-30 CN disclosed
CN-112400024-B Device and system for gastrointestinal microbiome detection and processing 比奥拉治疗股份有限公司 2024-04-09 CN disclosed
US-20230041197-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH AN IMMUNOMODULATOR GLAS USA LLC 2023-02-09 US disclosed
US-20230019619-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A TLR MODULATOR GLAS USA LLC 2023-01-19 US disclosed
US-11547301-B2 Methods for collecting and testing bacteria containing samples from within the gastrointestinal tract BIORA THERAPEUTICS, INC. (US) 2023-01-10 US disclosed
EP-4108183-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH AN IMMUNE MODULATORY AGENT RELEASED USING AN INGESTIBLE DEVICE Biora Therapeutics, Inc. (US) 2022-12-28 EP disclosed
US-11523772-B2 Treatment of a disease of the gastrointestinal tract with an immunosuppressant BIORA THERAPEUTICS, INC. (US) 2022-12-13 US disclosed
US-11426566-B2 Treatment of a disease of the gastrointestinal tract with a TLR modulator BIORA THERAPEUTICS, INC. (US) 2022-08-30 US disclosed
US-20220135666-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A S1P MODULATOR GLAS USA LLC 2022-05-05 US disclosed
WO-2022087313-A1 METHODS OF TREATING AND PREDICTING NON-RESPONSE TO ANTI-TNF TREATMENT IN SUBJECTS WITH GASTROINTESTINAL TRACT DISEASES PROGENITY, INC. (US) 2022-04-28 WO disclosed
US-20220071559-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH AN IMMUNOSUPPRESSANT GLAS USA LLC 2022-03-10 US disclosed
US-20220071894-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A CHEMOKINE/CHEMOKINE RECEPTOR INHIBITOR BT BIDCO LLC 2022-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230019619-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A TLR MODULATOR TLR6, TLR5, TLR9 MME 2495/4885ECE1 4291/4885CTSK 1461/4885
US-12089916-B2 Gastrointestinal tract detection methods, devices and systems FABP2, SI, MLNR MME 611/4885ECE1 1479/4885CTSK 355/4885
US-20230041197-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH AN IMMUNOMODULATOR FABP2, IL2, TSLP MME 1110/4885ECE1 4102/4885CTSK 778/4885
US-11426566-B2 Treatment of a disease of the gastrointestinal tract with a TLR modulator TLR6, TLR5, TLR9 MME 2495/4885ECE1 4291/4885CTSK 1461/4885
US-11547301-B2 Methods for collecting and testing bacteria containing samples from within the gastrointestinal tract SI, VIP, MLN MME 1565/4885ECE1 1998/4885CTSK 205/4885
US-20250082265-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH AN IMMUNOSUPPRESSANT TPMT, FABP2, SLC10A2 MME 1459/4885ECE1 3732/4885CTSK 960/4885
US-20220071894-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A CHEMOKINE/CHEMOKINE RECEPTOR INHIBITOR ACKR3, CXCR2, CXCR3 MME 681/4885ECE1 1416/4885CTSK 689/4885
US-20240335644-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH AN IMMUNE MODULATORY AGENT RELEASED USING AN INGESTIBLE DEVICE CD40LG, CD40, ICOS MME 1105/4885ECE1 1408/4885CTSK 413/4885
US-20220135666-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A S1P MODULATOR S1PR2, S1PR1, S1PR4 MME 1686/4885ECE1 1255/4885CTSK 888/4885
US-20250000364-A1 GASTROINTESTINAL TRACT DETECTION METHODS, DEVICES AND SYSTEMS FABP2, SI, MLNR MME 611/4885ECE1 1479/4885CTSK 355/4885
US-20220071559-A1 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH AN IMMUNOSUPPRESSANT TPMT, FABP2, SLC10A2 MME 1459/4885ECE1 3732/4885CTSK 960/4885
US-11523772-B2 Treatment of a disease of the gastrointestinal tract with an immunosuppressant TPMT, FABP2, SLC10A2 MME 1459/4885ECE1 3732/4885CTSK 960/4885
US-12150775-B2 Treatment of a disease of the gastrointestinal tract with an immunosuppressant TPMT, FABP2, SLC10A2 MME 1459/4885ECE1 3732/4885CTSK 960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.