Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3705296 | 0.92 | NAMPT (0.34) | NAMPTABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL3808574 | 0.92 | ABCC9 (0.35) | NAMPTABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL3699028 | 0.91 | PTGDR2 (0.34) | ABCC9ABCC8KCNJ11KCNJ8PTGER2 | |
| SCHEMBL3699813 | 0.88 | ABCC9 (0.34) | NAMPTABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL3695804 | 0.88 | ABCC9 (0.34) | NAMPTABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL3701318 | 0.88 | NAMPT (0.36) | NAMPTABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL4126972 | 0.87 | NAMPT (0.36) | NAMPTABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL3700979 | 0.86 | KCNQ3 (0.34) | ALDH1A1KDM4EMAPTCNR2 | |
| Hydrochloric Acid SCHEMBL3707039 | 0.86 | ABCC9 (0.33) | NAMPTABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL4566348 | 0.85 | PTGER2 (0.33) | ABCC9ABCC8KCNJ11KCNJ8TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009041705-A9 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009041705-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-02 | — | — | WO | disclosed |