Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 15/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.33 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3706681 | 0.92 | — | — | |
| SCHEMBL3695804 | 0.92 | ABCC9 (0.34) | PTGER2ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL3688572 | 0.90 | RIPK1 (0.34) | RIPK1 | |
| SCHEMBL3705296 | 0.89 | NAMPT (0.34) | PTGER2TAS2R14ABCC9ABCC8KCNJ11 | |
| SCHEMBL3699813 | 0.89 | ABCC9 (0.34) | PTGER2ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL3808574 | 0.88 | ABCC9 (0.35) | PTGER2ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL4123658 | 0.88 | TAS2R14 (0.35) | PTGER2TAS2R14RIPK1HTT | |
| SCHEMBL3693161 | 0.85 | NAMPT (0.36) | PTGER2TAS2R14ABCC9ABCC8KCNJ11 | |
| SCHEMBL3701318 | 0.85 | NAMPT (0.36) | PTGER2ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL3703103 | 0.84 | NAMPT (0.33) | PTGER2ABCC9ABCC8KCNJ11KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009041705-A9 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL (JP) | 2009-08-13 | — | — | WO | disclosed |