Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 3/20 | 0.37 |
| ▸ | CASP3 | P42574 | 3/20 | 0.37 |
| ▸ | CASP9 | P55211 | 3/20 | 0.37 |
| ▸ | CYCS | P99999 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3693131 | 0.92 | HTR2A (0.36) | MAPTAPAF1CASP3CASP9CYCS | |
| SCHEMBL3700997 | 0.92 | APAF1 (0.38) | MAPTSMN1; SMN2APAF1CASP3CASP9 | |
| SCHEMBL3694367 | 0.89 | APAF1 (0.44) | MAPTSMN1; SMN2RAB9AAPAF1CASP3 | |
| SCHEMBL3701029 | 0.87 | TACR2 (0.45) | MAPTSMN1; SMN2APAF1CASP3CASP9 | |
| SCHEMBL3700838 | 0.87 | APAF1 (0.36) | MAPTSMN1; SMN2APAF1CASP3CASP9 | |
| SCHEMBL3698185 | 0.86 | MAPT (0.36) | MAPTSMN1; SMN2APAF1CASP3CASP9 | |
| SCHEMBL9280399 | 0.86 | MAPT (0.37) | MAPTSMN1; SMN2RAB9ANPSR1CYP3A4 | |
| SCHEMBL3703380 | 0.85 | SMN1; SMN2 (0.43) | MAPTSMN1; SMN2RAB9AAPAF1CASP3 | |
| SCHEMBL3702485 | 0.85 | CA12 (0.37) | MAPTSMN1; SMN2APAF1CASP3CASP9 | |
| SCHEMBL3698794 | 0.85 | SMN1; SMN2 (0.42) | MAPTSMN1; SMN2RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040701-B2 | Apaf-1 inhibitor compounds | LABORATORIOS SALVAT, S.A. (ES) | 2015-05-26 | — | — | US | disclosed |
| US-20120122868-A1 | APAF-1 INHIBITOR COMPOUNDS | LABORATORIOS SALVAT, S.A. (ES) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122868-A1 | APAF-1 INHIBITOR COMPOUNDS | APAF1, API5, AIFM1 | MAPT 4448/4885SMN1; SMN2 2020/4885RAB9A 3904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.