Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 5/20 | 0.45 |
| ▸ | MC4R | P32245 | 2/20 | 0.37 |
| ▸ | MC5R | P33032 | 2/20 | 0.37 |
| ▸ | MC3R | P41968 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 3/20 | 0.36 |
| ▸ | CASP3 | P42574 | 3/20 | 0.36 |
| ▸ | CASP9 | P55211 | 3/20 | 0.36 |
| ▸ | CYCS | P99999 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3697589 | 0.92 | BCHE (0.37) | TACR2ACHEKDM4E | |
| SCHEMBL3700997 | 0.89 | APAF1 (0.38) | MC4RMC5RMC3RAPAF1CASP3 | |
| SCHEMBL3705051 | 0.89 | APAF1 (0.36) | TACR2APAF1CASP3CASP9CYCS | |
| SCHEMBL3693162 | 0.87 | MAPT (0.37) | APAF1CASP3CASP9CYCSDRD2 | |
| SCHEMBL3697424 | 0.87 | APAF1 (0.34) | TACR2APAF1CASP3CASP9CYCS | |
| SCHEMBL9105301 | 0.87 | TACR2 (0.42) | TACR2MC4RMC5RMC3RHRH3 | |
| SCHEMBL3705169 | 0.86 | ALDH1A1 (0.36) | TACR2APAF1CASP3CASP9CYCS | |
| SCHEMBL9101546 | 0.85 | C5AR1 (0.39) | TACR2APAF1CASP3CASP9CYCS | |
| SCHEMBL3696385 | 0.85 | PTGS2 (0.37) | HRH3APAF1CASP3CASP9CYCS | |
| SCHEMBL3701027 | 0.84 | APAF1 (0.53) | TACR2MC4RMC5RMC3RAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040701-B2 | Apaf-1 inhibitor compounds | LABORATORIOS SALVAT, S.A. (ES) | 2015-05-26 | — | — | US | disclosed |
| US-20120122868-A1 | APAF-1 INHIBITOR COMPOUNDS | LABORATORIOS SALVAT, S.A. (ES) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122868-A1 | APAF-1 INHIBITOR COMPOUNDS | APAF1, API5, AIFM1 | TACR2 4560/4885MC4R 4827/4885MC5R 4593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.