Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 7/20 | 0.65 |
| ▸ | LMNA | P02545 | 5/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.65 |
| ▸ | HTR2A | P28223 | 4/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.65 |
| ▸ | HTR2B | P41595 | 3/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.65 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.65 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.65 |
| ▸ | DRD1 | P21728 | 3/20 | 0.65 |
| ▸ | HTR2C | P28335 | 3/20 | 0.65 |
| ▸ | DRD3 | P35462 | 3/20 | 0.65 |
| ▸ | HTR3A | P46098 | 3/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.65 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.65 |
| ▸ | CNR1 | P21554 | 2/20 | 0.65 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.65 |
| ▸ | DRD2 | P14416 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850494 | 0.89 | HRH1 (0.76) | HRH1LMNACHRM2HTR2AOPRK1 | |
| SCHEMBL3040909 | 0.85 | HRH1 (0.59) | HRH1LMNACHRM2HTR2AOPRK1 | |
| SCHEMBL25685848 | 0.83 | HRH1 (0.69) | HRH1LMNACHRM2HTR2AOPRK1 | |
| SCHEMBL3042922 | 0.82 | HRH1 (0.58) | HRH1LMNACHRM2HTR2AOPRK1 | |
| SCHEMBL14693597 | 0.82 | HRH1 (0.58) | HRH1LMNACHRM2HTR2AOPRK1 | |
| SCHEMBL3704516 | 0.82 | HRH1 (0.58) | HRH1LMNACHRM2HTR2AOPRK1 | |
| SCHEMBL9631337 | 0.80 | HRH1 (0.62) | HRH1LMNACHRM2HTR2AOPRK1 | |
| Pizotyline SCHEMBL8771138 | 0.79 | DRD1 (1.00) | HRH1LMNACHRM2HTR2AOPRK1 | |
| Pizotyline SCHEMBL29366884 | 0.79 | DRD1 (1.00) | HRH1LMNACHRM2HTR2AOPRK1 | |
| Pizotyline SCHEMBL44122 | 0.79 | DRD1 (1.00) | HRH1LMNACHRM2HTR2AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460803-B1 | METHOD FOR PRODUCING THIABENZOAZULENE PROPIONIC ACID DERIVATIVE | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2016-01-13 | — | — | EP | disclosed |
| US-8536342-B2 | Process for producing thiabenzoazulene-propionic acid derivative | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2013-09-17 | — | — | US | disclosed |
| EP-2460803-A1 | METHOD FOR PRODUCING THIABENZOAZULENE PROPIONIC ACID DERIVATIVE | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2012-06-06 | — | — | EP | disclosed |
| US-20120123127-A1 | PROCESS FOR PRODUCING THIABENZOAZULENE-PROPIONIC ACID DERIVATIVE | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123127-A1 | PROCESS FOR PRODUCING THIABENZOAZULENE-PROPIONIC ACID DERIVATIVE | HRH4, HRH2, HRH1 | HRH1 3/4885LMNA 4056/4885CHRM2 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.