Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3694806 | 1.00 | MEN1 (0.40) | MEN1KMT2AKDM4EL3MBTL1GAA | |
| SCHEMBL3708687 | 1.00 | MEN1 (0.40) | MEN1KMT2AKDM4EL3MBTL1GAA | |
| SCHEMBL31525035 | 0.74 | HSD17B10 (0.47) | MEN1KMT2AKDM4EL3MBTL1GAA | |
| SCHEMBL3253975 | 0.74 | HSD17B10 (0.47) | MEN1KMT2AKDM4EL3MBTL1GAA | |
| SCHEMBL11098511 | 0.72 | KMT2A (0.48) | MEN1KMT2AKDM4EMAPTHSD17B10 | |
| SCHEMBL11098513 | 0.72 | KMT2A (0.48) | MEN1KMT2AKDM4EMAPTHSD17B10 | |
| SCHEMBL12278880 | 0.72 | ALDH1A1 (0.42) | MEN1KMT2AKDM4EL3MBTL1GAA | |
| SCHEMBL1065970 | 0.72 | MEN1 (0.47) | MEN1KMT2AKDM4EL3MBTL1GAA | |
| SCHEMBL28316412 | 0.72 | ALDH1A1 (0.47) | MEN1KMT2AKDM4EL3MBTL1GAA | |
| SCHEMBL7335158 | 0.70 | HSP90AA1 (0.49) | MEN1KMT2AKDM4EL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2043995-B1 | A METHOD FOR PRODUCING ALKENYL NITROBENZOL DERIVATIVES UNBRANCHED IN THE 1-POSITION | BAYER CROPSCIENCE AG (DE) | 2013-01-02 | — | — | EP | disclosed |
| EP-1858837-B1 | PROCESS FOR THE PRODUCTION OF 2-(2-AMINOPHENYL)-BICYCLOPROPANE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-16 | — | — | EP | disclosed |
| US-8071824-B2 | Method for producing alkenylnitrobenzene derivatives unbranched in the 1′-position | BAYER CROPSCIENCE AG (DE) | 2011-12-06 | — | — | US | disclosed |
| US-8071824-B2 | Method for producing alkenylnitrobenzene derivatives unbranched in the 1′-position | BAYER CROPSCIENCE AG (DE) | 2011-12-06 | — | — | US | disclosed |
| US-20110237836-A1 | Method for Producing Alkylnitrobenzenes and Alkylanilines, Unbranched in the 1'-Position, from Nitrotoluenes | BAYER CROPSCIENCE AG (DE) | 2011-09-29 | — | — | US | disclosed |
| US-20100076229-A1 | Method for Producing Alkenylnitrobenzene Derivatives Unbranched in the 1'-Position | BAYER CROPSCIENCE AG (DE) | 2010-03-25 | — | — | US | disclosed |
| US-7514584-B2 | Process for the production of 2(2-aminophenyl)-bicylopropane derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2009-04-07 | — | — | US | disclosed |
| US-20080161610-A1 | Process For the Production of 2(2-Aminophenyl)-Bicylopropane Derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2008-07-03 | — | — | US | disclosed |
| WO-2008006576-A1 | A METHOD FOR PRODUCING ALKENYL NITROBENZOL DERIVATIVES UNBRANCHED IN THE 1-POSITION | BAYER CROPSCIENCE AG (DE) | 2008-01-17 | — | — | WO | disclosed |
| EP-1858837-A1 | PROCESS FOR THE PRODUCTION OF 2-(2-AMINOPHENYL)-BICYCLOPROPANE DERIVATIVES | Syngeta Participations AG (CH) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006087223-A1 | PROCESS FOR THE PRODUCTION OF 2- (2-AMINOPHENYL)-BICYCLOPROPANE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-08-24 | — | — | WO | disclosed |
| WO-2006087222-A1 | PROCESS FOR THE PRODUCTION OF NITROBENZOLES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-08-24 | — | — | WO | disclosed |
| WO-2006087221-A1 | PROCESS FOR THE PRODUCTION OF NITROBENZOLES | SYNGENTA PARTICIPATIONS AG (CH) | 2006-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237836-A1 | Method for Producing Alkylnitrobenzenes and Alkylanilines, Unbranched in the 1'-Position, from Nitrotoluenes | CYP1B1, CYP1A1, CYP1A2 | MEN1 2949/4885KMT2A 1543/4885KDM4E 1680/4885 |
| US-20100076229-A1 | Method for Producing Alkenylnitrobenzene Derivatives Unbranched in the 1'-Position | CYP1B1, AKR7A2, CYP1A1 | MEN1 2748/4885KMT2A 1165/4885KDM4E 1314/4885 |
| US-20080161610-A1 | Process For the Production of 2(2-Aminophenyl)-Bicylopropane Derivatives | CYP1B1, CYP4B1, MAOB | MEN1 922/4885KMT2A 3113/4885KDM4E 1767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.