Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.38 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.38 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2412821 | 0.86 | TBXAS1 (0.44) | TBXAS1SMN1; SMN2NAPRTCFTRSLC6A2 | |
| SCHEMBL7824306 | 0.83 | ALOX15 (0.41) | L3MBTL1CYP2C19 | |
| Acetic Acid SCHEMBL27871968 | 0.74 | LMNA (0.42) | TBXAS1PLA2G7MGLLABHD6SMN1; SMN2 | |
| SCHEMBL17541025 | 0.74 | CFTR (0.42) | PLA2G7MGLLABHD6SMN1; SMN2NAPRT | |
| SCHEMBL13829487 | 0.74 | CFTR (0.42) | PLA2G7MGLLABHD6SMN1; SMN2NAPRT | |
| SCHEMBL15579711 | 0.73 | SLC6A2 (0.44) | PLA2G7MGLLABHD6SMN1; SMN2CFTR | |
| SCHEMBL15579729 | 0.73 | SLC6A2 (0.44) | PLA2G7MGLLABHD6SMN1; SMN2CFTR | |
| SCHEMBL12199685 | 0.73 | SLC6A2 (0.44) | PLA2G7MGLLABHD6SMN1; SMN2CFTR | |
| SCHEMBL12199164 | 0.73 | SLC6A2 (0.44) | PLA2G7MGLLABHD6SMN1; SMN2CFTR | |
| SCHEMBL15579732 | 0.73 | SLC6A2 (0.44) | PLA2G7MGLLABHD6SMN1; SMN2CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593425-A1 | THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHOD OF USE | Agios Pharmaceuticals, Inc. (US) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012009678-A1 | THERAPEUTICALLY ACTIVE COMPOSITIONS AND THEIR METHOD OF USE | AGIOS PHARMACEUTICALS, INC. (US) | 2012-01-19 | — | — | WO | disclosed |