Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16274185 | 0.91 | RECQL (0.43) | RECQLPKMALDH1A1NPC1RAB9A | |
| SCHEMBL1611209 | 0.88 | HTT (0.41) | RECQLPKMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28971266 | 0.87 | RECQL (0.36) | RECQLPKMALDH1A1CA1CA2 | |
| SCHEMBL3123277 | 0.87 | HTT (0.43) | RECQLPKMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1611047 | 0.87 | RECQL (0.36) | RECQLPKMHTTABL1RIN1 | |
| SCHEMBL3695100 | 0.87 | RECQL (0.44) | RECQLPKMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3111479 | 0.86 | RECQL (0.34) | RECQLPKMCA1CA2 | |
| SCHEMBL3358580 | 0.86 | RECQL (0.32) | RECQLPKMCA1CA2 | |
| SCHEMBL112195 | 0.86 | CA1 (0.32) | RECQLPKMCA1CA2 | |
| SCHEMBL1611478 | 0.86 | CA1 (0.32) | RECQLPKMCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9073910-B2 | 5-aryl isoxazolines for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-07-07 | — | — | US | disclosed |
| EP-2360157-B1 | 5-aryl isoxazolines for controlling invertebrate pests | DU PONT (US) | 2012-11-21 | — | — | EP | disclosed |
| US-20120053051-A9 | 5-ARYL ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-01 | — | — | US | disclosed |
| EP-1975149-B1 | 1,3-BIS(SUBSTITUTED PHENYL)-3-HYDROXYPROPAN-1-ONE OR 2-PROPEN-1-ONE COMPOUND, AND SALT THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2012-02-15 | — | — | EP | disclosed |
| EP-2360157-A1 | 5-aryl isoxazolines for controlling invertebrate pests | E. I. du Pont de Nemours and Company (US) | 2011-08-24 | — | — | EP | disclosed |
| US-20110152081-A1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-06-23 | — | — | US | disclosed |
| US-7897630-B2 | 5-aryl isoxazolines for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-03-01 | — | — | US | disclosed |
| US-7700808-B2 | 1-3-bis(substituted phenyl)-3-hydroxypropan-1-one or 2-propen-1-one compound, and salt thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-04-20 | — | — | US | disclosed |
| US-20090133319-A1 | 5-Aryl Isoxazolines for Controlling Invertebrate Pests | E. I. DU PONT DE NEMOURS AND COMPANY (DE) | 2009-05-28 | — | — | US | disclosed |
| US-20090023923-A1 | 1,3-Bis(Substituted Phenyl)-3-Hydroxypropan-1-One or 2-Propen-1-One Compound, and Salt Thereof | NISSAN CHEMICAL INDUSTRIES, LTD (JP) | 2009-01-22 | — | — | US | disclosed |
| EP-1975149-A1 | 1,3-BIS(SUBSTITUTED PHENYL)-3-HYDROXYPROPAN-1-ONE OR 2-PROPEN-1-ONE COMPOUND, AND SALT THEREOF | Nissan Chemical Industries, Ltd. (JP) | 2008-10-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053051-A9 | 5-ARYL ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | PRXL2A, C5, CBR3 | RECQL 695/4885PKM 4748/4885ALDH1A1 2079/4885 |
| US-20090023923-A1 | 1,3-Bis(Substituted Phenyl)-3-Hydroxypropan-1-One or 2-Propen-1-One Compound, and Salt Thereof | HCN1, CNPY2, CLIC1 | RECQL 3888/4885PKM 3297/4885ALDH1A1 696/4885 |
| US-20090133319-A1 | 5-Aryl Isoxazolines for Controlling Invertebrate Pests | PRXL2A, C5, CBR3 | RECQL 693/4885PKM 4703/4885ALDH1A1 2520/4885 |
| US-20110152081-A1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS | PRXL2A, C5, CBR3 | RECQL 695/4885PKM 4748/4885ALDH1A1 2079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.