Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 1/20 | 0.31 |
| ▸ | ELOC | Q15369 | 1/20 | 0.31 |
| ▸ | ELOB | Q15370 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18392229 | 0.57 | POLB (0.38) | VHLELOCELOBMAPTKDM4E | |
| SCHEMBL694208 | 0.57 | MAPT (0.40) | VHLELOCELOBMAPTKDM4E | |
| SCHEMBL60890 | 0.57 | VHL (0.44) | VHLELOCELOBMAPTKDM4E | |
| SCHEMBL44284 | 0.56 | KDM4E (0.50) | VHLELOCELOBMAPTKDM4E | |
| SCHEMBL20319187 | 0.55 | MAPT (0.68) | VHLELOCELOBMAPTKDM4E | |
| SCHEMBL208956 | 0.55 | — | — | |
| SCHEMBL13661859 | 0.53 | KDM4E (0.36) | VHLELOCELOBMAPTKDM4E | |
| SCHEMBL1551099 | 0.52 | — | — | |
| SCHEMBL196307 | 0.51 | NOTUM (0.52) | VHLELOCELOBMAPTKDM4E | |
| SCHEMBL5604589 | 0.51 | MAPT (0.44) | VHLELOCELOBMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489818-A1 | THREONINE DERIVED ASYMMETRIC CHEMICAL SYNTHESIS AND INTERMEDIATES FOR MAKING ANTIFUNGAL COMPOUNDS | SCHERING CORPORATION (US) | 1992-06-17 | — | — | EP | claimed |
| WO-1991003473-A1 | THREONINE DERIVED ASYMMETRIC CHEMICAL SYNTHESIS AND INTERMEDIATES FOR MAKING ANTIFUNGAL COMPOUNDS | SCHERING CORPORATION (US) | 1991-03-21 | — | — | WO | claimed |
| EP-0415748-A1 | Threonine derived asymmetric chemical synthesis and intermediates for making antifungal compounds | SCHERING CORPORATION (US) | 1991-03-06 | — | — | EP | claimed |
| CN-101817784-B | Ethylene derivatives and pesticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES CO., LTD. (JP) | 2012-02-01 | — | — | CN | disclosed |
| EP-1720063-B1 | Resin containing ketene-aldehyde copolymer | NIPPON SODA CO (JP) | 2010-04-07 | — | — | EP | disclosed |
| EP-1482361-B1 | ACID-DEGRADABLE RESIN COMPOSITIONS CONTAINING KETENE-ALDEHYDE COPOLYMER | NIPPON SODA CO (JP) | 2007-10-03 | — | — | EP | disclosed |
| EP-1720063-A1 | Resin containing ketene-aldehyde copolymer | NIPPON SODA CO., LTD. (JP) | 2006-11-08 | — | — | EP | disclosed |
| US-7105272-B2 | Acid-degradable resin compositions containing ketene-aldehyde copolymer | NIPPON SODA CO., LTD. (JP) | 2006-09-12 | — | — | US | disclosed |
| US-20050130057-A1 | Acid-degradable resin compositions containing ketene-aldehyde copolymer | NIPPON SODA CO., LTD. (JP) | 2005-06-16 | — | — | US | disclosed |
| EP-1482361-A1 | ACID-DEGRADABLE RESIN COMPOSITIONS CONTAINING KETENE-ALDEHYDE COPOLYMER | NIPPON SODA CO., LTD. (JP) | 2004-12-01 | — | — | EP | disclosed |
| EP-0913392-B1 | ETHYLENE DERIVATIVES AND PEST CONTROLLING AGENTS | NISSAN CHEMICAL IND LTD (JP) | 2003-07-02 | — | — | EP | disclosed |
| EP-0913392-A4 | ETHYLENE DERIVATIVES AND PEST CONTROLLING AGENTS | NISSAN CHEMICAL IND LTD (JP) | 1999-12-15 | — | — | EP | disclosed |
| WO-1997040009-A1 | ETHYLENE DERIVATIVES AND PEST CONTROLLING AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |
| EP-0489818-A1 | THREONINE DERIVED ASYMMETRIC CHEMICAL SYNTHESIS AND INTERMEDIATES FOR MAKING ANTIFUNGAL COMPOUNDS | SCHERING CORPORATION (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0489804-A1 | ASYMMETRIC CHEMICAL SYNTHESIS AND INTERMEDIATES FOR MAKING ANTIFUNGAL COMPOUNDS | SCHERING CORPORATION (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0421600-A1 | Asymmetric chemical synthesis and intermediates for making antifungal compounds | SCHERING CORPORATION (US) | 1991-04-10 | — | — | EP | disclosed |
| WO-1991003473-A1 | THREONINE DERIVED ASYMMETRIC CHEMICAL SYNTHESIS AND INTERMEDIATES FOR MAKING ANTIFUNGAL COMPOUNDS | SCHERING CORPORATION (US) | 1991-03-21 | — | — | WO | disclosed |
| WO-1991003451-A1 | ASYMMETRIC CHEMICAL SYNTHESIS AND INTERMEDIATES FOR MAKING ANTIFUNGAL COMPOUNDS | SCHERING CORPORATION (US) | 1991-03-21 | — | — | WO | disclosed |
| EP-0415748-A1 | Threonine derived asymmetric chemical synthesis and intermediates for making antifungal compounds | SCHERING CORPORATION (US) | 1991-03-06 | — | — | EP | disclosed |