SCHEMBL5604589

SCHEMBL5604589

Cc1cc(C)cc(-n2cccc2)c1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.44
ALDH1A1 P00352 3/20 0.41
HSP90AA1 P07900 1/20 0.41
CCR6 P51684 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.39
KDM4E B2RXH2 2/20 0.39
GAA P10253 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HPGD P15428 1/20 0.39
POLB P06746 2/20 0.38
APP P05067 1/20 0.37
NOTUM Q6P988 1/20 0.37
ACHE P22303 1/20 0.36
TSHR P16473 1/20 0.36
COMT P21964 1/20 0.35
VHL P40337 1/20 0.34
ELOC Q15369 1/20 0.34
ELOB Q15370 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26569849 0.94 MAPT (0.39) MAPTALDH1A1HSP90AA1CCR6L3MBTL1
SCHEMBL3466782 0.89 ALDH1A1 (0.52) MAPTALDH1A1HSP90AA1CCR6L3MBTL1
SCHEMBL1966595 0.77 MAPT (0.56) MAPTALDH1A1HSP90AA1L3MBTL1KDM4E
SCHEMBL12369610 0.74 CHRNB2 (0.44) MAPTL3MBTL1KDM4EGAANPSR1
SCHEMBL1366622 0.72 L3MBTL1 (0.56) MAPTALDH1A1L3MBTL1KDM4EGAA
SCHEMBL28278816 0.72 HSP90AA1 (0.41) MAPTALDH1A1HSP90AA1CCR6L3MBTL1
SCHEMBL2960961 0.70 POLB (0.39) MAPTALDH1A1L3MBTL1KDM4EGAA
SCHEMBL17059032 0.67 COMT (0.49) MAPTALDH1A1HSP90AA1CCR6L3MBTL1
Benzene SCHEMBL3435383 0.67 ACHE (0.57) MAPTALDH1A1HSP90AA1CCR6ACHE
SCHEMBL9337373 0.67 MAPT (0.39) MAPTALDH1A1L3MBTL1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105218711-B A kind of double activated component olefin polymerization catalysis and preparation method 淄博新塑化工有限公司 2017-08-25 CN claimed
CN-105218711-A A kind of double activated component olefin polymerization catalysis and preparation method ZIBO XINSU CHEMICAL CO LTD 2016-01-06 CN claimed
CN-1074933-C Anti-stress, anti-impairment and anti-aging drug and process for manufacturing thereof RIGA D (RO) 2001-11-21 CN claimed
CN-119899436-A High-temperature-resistant flame-retardant protective shoe and preparation method thereof 中海油安全技术服务有限公司 2025-04-29 CN disclosed
US-20230337525-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
CN-110201721-A Complex compound 庄信万丰股份有限公司 2019-09-06 CN disclosed
CN-105218711-B A kind of double activated component olefin polymerization catalysis and preparation method 淄博新塑化工有限公司 2017-08-25 CN disclosed
CN-106661071-A Complex compounds 庄信万丰股份有限公司 2017-05-10 CN disclosed
EP-1390340-B1 COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS MASSACHUSETTS INST TECHNOLOGY (US) 2017-03-01 EP disclosed
EP-1390340-B1 COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS MASSACHUSETTS INST TECHNOLOGY (US) 2017-03-01 EP disclosed
CN-105218711-A A kind of double activated component olefin polymerization catalysis and preparation method ZIBO XINSU CHEMICAL CO LTD 2016-01-06 CN disclosed
US-20050215794-A1 Copper-catalyzed formation of carbon heteroatom and carbon-carbon bonds NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-09-29 US disclosed
US-6867298-B2 Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2005-03-15 US disclosed
CN-1518534-A Copper-catalyzed carbon-heteroatom and carbon-carbon bond formation 麻省理工学院 2004-08-04 CN disclosed
US-6759554-B2 Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2004-07-06 US disclosed
EP-1390340-A1 COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2004-02-25 EP disclosed
US-20040019216-A1 Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2004-01-29 US disclosed
US-20030065187-A1 Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-04-03 US disclosed
WO-2002085838-A1 COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2002-10-31 WO disclosed
CN-1074933-C Anti-stress, anti-impairment and anti-aging drug and process for manufacturing thereof RIGA D (RO) 2001-11-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050215794-A1 Copper-catalyzed formation of carbon heteroatom and carbon-carbon bonds CBR3, ADH5, IDH1 MAPT 2527/4885ALDH1A1 30/4885HSP90AA1 3261/4885
US-20030065187-A1 Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds ADH5, CBR3, ALDH3A1 MAPT 2654/4885ALDH1A1 26/4885HSP90AA1 3140/4885
US-20040019216-A1 Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds ADH5, CBR3, ALDH3A1 MAPT 2654/4885ALDH1A1 26/4885HSP90AA1 3140/4885
US-20230337525-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OXER1 MAPT 773/4885ALDH1A1 60/4885HSP90AA1 4731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.