SCHEMBL196307

SCHEMBL196307

Clc1ccc(-n2cccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 3/20 0.52
POLB P06746 2/20 0.52
VHL P40337 1/20 0.50
ELOC Q15369 1/20 0.50
ELOB Q15370 1/20 0.50
KDM4E B2RXH2 1/20 0.50
GAA P10253 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
MAPT P10636 3/20 0.46
NPC1 O15118 1/20 0.46
ALDH1A1 P00352 1/20 0.46
CYP1A2 P05177 1/20 0.46
HTT P42858 1/20 0.46
RAB9A P51151 1/20 0.46
LMNA P02545 2/20 0.46
ALOX12 P18054 1/20 0.46
NLRP1 Q9C000 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4919323 0.79 MAPT (0.56) MEN1KMT2AMAPTNPC1ALDH1A1
SCHEMBL11625350 0.77 KMT2A (0.53) NOTUMPOLBNPSR1MEN1KMT2A
SCHEMBL44284 0.73 KDM4E (0.50) POLBVHLELOCELOBKDM4E
SCHEMBL636960 0.72 VHL (0.50) POLBVHLELOCELOBKDM4E
SCHEMBL296099 0.72 MAPT (0.56) POLBVHLELOCELOBKDM4E
SCHEMBL599252 0.72 VHL (0.56) POLBVHLELOCELOBKDM4E
SCHEMBL11822364 0.72 KDM4E (0.50) POLBVHLELOCELOBKDM4E
SCHEMBL393880 0.72 KDM4E (0.50) POLBVHLELOCELOBKDM4E
SCHEMBL5547132 0.72 KDM4E (0.50) POLBVHLELOCELOBKDM4E
SCHEMBL1260035 0.72 KDM4E (0.50) POLBVHLELOCELOBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110105287-A A kind of synthesis technology of pyraclostrobin 江苏禾本生化有限公司 2019-08-09 CN claimed
CN-1232520-C Salts of bicyclic N-acylated imidazol-3-amines and imidazol-5-amines GRUENENTHAL GMBH (DE) 2005-12-21 CN claimed
CN-1211385-C Bicyclic imidazo-5-yl-amine derivs. GRUENENTHAL GMBH (DE) 2005-07-20 CN claimed
CN-1422270-A Salts of bicyclic N-acylated imidazol-3-amines and imidazol-5-amines GRUELENTHAL GMBH (DE) 2003-06-04 CN claimed
JP-2003511456-A 2003-03-25 JP claimed
CN-1402726-A Bicyclic imidazo-5-yl-amine derivs. GRUENENTHAL GMBH (DE) 2003-03-12 CN claimed
EP-1218383-A2 BICYCLIC IMIDAZO-5-YL-AMINE DERIVATIVES Grünenthal GmbH (DE) 2002-07-03 EP claimed
WO-2001027118-A2 BICYCLIC IMIDAZO-5-YL-AMINE DERIVATIVES Grünenthal GmbH (DE) 2001-04-19 WO claimed
US-20250312367-A1 OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF ADARX PHARMACEUTICALS, INC. (US) 2025-10-09 US disclosed
US-12391781-B2 Black particles, black coating material, coating film, and black matrix for color filters SEKISUI CHEMICAL CO., LTD. (JP) 2025-08-19 US disclosed
EP-4063426-B1 BLACK PARTICLES, BLACK COATING MATERIAL, COATING FILM, AND BLACK MATRIX FOR COLOR FILTERS SEKISUI CHEMICAL CO LTD (JP) 2025-06-18 EP disclosed
WO-2025073702-A1 PROCESS FOR PREPARING AROMATIC AMINES FROM ARYL CHLORIDES BASF SE (DE) 2025-04-10 WO disclosed
EP-4522628-A2 OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF Adarx Pharmaceuticals, Inc. (US) 2025-03-19 EP disclosed
CN-119485936-A Flame-retardant flexible circuit board and preparation method thereof 德兴市恒海科技有限公司 2025-02-18 CN disclosed
CN-1187326-C Novel compounds ASTRAZENECA AB (SE) 2005-02-02 CN disclosed
CN-1426393-A Novel compounds ASTRAZENECA AB (SE) 2003-06-25 CN disclosed
CN-1426412-A Novel compounds ASTRAZENECA AB (SE) 2003-06-25 CN disclosed
CN-1426394-A Novel compounds ASTRAZENECA AB (SE) 2003-06-25 CN disclosed
CN-1422270-A Salts of bicyclic N-acylated imidazol-3-amines and imidazol-5-amines GRUELENTHAL GMBH (DE) 2003-06-04 CN disclosed
CN-1402726-A Bicyclic imidazo-5-yl-amine derivs. GRUENENTHAL GMBH (DE) 2003-03-12 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250312367-A1 OLIGONUCLEOTIDES HAVING A SYNTHETIC BACKBONE AND SYNTHESIS THEREOF POLRMT, TARDBP, NSUN2 NOTUM 4490/4885POLB 20/4885VHL 842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.