⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11715676 | 0.98 | TSHR (0.42) | — | |
| SCHEMBL11726606 | 0.83 | AKR1B1 (0.42) | — | |
| SCHEMBL5062781 | 0.79 | — | — | |
| SCHEMBL19159756 | 0.79 | — | — | |
| SCHEMBL11728665 | 0.79 | AKR1B1 (0.58) | — | |
| SCHEMBL12094828 | 0.76 | MAPT (0.42) | — | |
| SCHEMBL1527228 | 0.76 | TSHR (0.48) | — | |
| SCHEMBL13040083 | 0.76 | ALDH1A1 (0.44) | — | |
| SCHEMBL10110775 | 0.76 | PGR (0.38) | — | |
| SCHEMBL22518504 | 0.74 | AOC2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112661688-B | Synthetic method of non-steroidal anti-inflammatory drug tolmetin | 杭州迪克科技有限公司 | 2023-04-07 | — | — | CN | claimed |
| US-20210375501-A1 | SELF-HEALING AND STRETCHABLE POLYMERIC COMPOSITIONS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA | 2021-12-02 | — | — | US | claimed |
| EP-4029868-B1 | MCL-1 INHIBITORS | GILEAD SCIENCES INC (US) | 2026-05-20 | — | — | EP | disclosed |
| EP-4737449-A1 | P53-Y220C SELECTIVE SMALL-MOLECULAR REACTIVATOR COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Changchun Genescience Pharmaceutical Co., Ltd. (CN) | 2026-05-06 | — | — | EP | disclosed |
| WO-2026090477-A1 | HELICASE INHIBITORS AND USES THEREOF | KIMIA THERAPEUTICS, INC. (US) | 2026-04-30 | — | — | WO | disclosed |
| US-12559462-B2 | Pyrimidine derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto | ARENA PHARMACEUTICALS, INC. (US) | 2026-02-24 | — | — | US | disclosed |
| US-20250270172-A1 | Pyrimidine Derivatives As Modulators of the 5-HT2A Serotonin Receptor Useful For The Treatment of Disorders Related Thereto | ARENA PHARMACEUTICALS, INC. (US) | 2025-08-28 | — | — | US | disclosed |
| EP-4236937-B1 | PYRIMIDINE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2025-07-23 | — | — | EP | disclosed |
| CN-119923385-A | Inhibitors of RNA helicase DHX9 and uses thereof | 埃克森特治疗公司 | 2025-05-02 | — | — | CN | disclosed |
| EP-3917527-B1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2025049820-A1 | STAT6 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |
| US-5661166-A | TREATING PEPTIC ULCERS | TOKYO TANABE CO. LTD. (JP) | 1997-08-26 | — | — | US | disclosed |
| EP-0771790-A1 | Process for preparing 1-substituted pyrrole-3-carboxylic acid derivatives | SUNTORY LIMITED (JP) | 1997-05-07 | — | — | EP | disclosed |
| EP-0623619-A1 | NEW ARENO[e]INDOLS, PREPARATION METHOD AND APPLICATION AS INTERMEDIATES IN THE SYNTHESIS OF PRODUCTS WITH ANTITUMORAL ACTIVITY | PHARMA-MAR S.A.-PHARMAR (ES) | 1994-11-09 | — | — | EP | disclosed |
| US-4563444-A | ANTITUMOR AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1986-01-07 | — | — | US | disclosed |
| US-4511575-A | Antidiabetic pyrrolecarboxylic acids | PFIZER INC. (US) | 1985-04-16 | — | — | US | disclosed |
| US-4511576-A | Antidiabetic pyrrolecarboxylic acids | PFIZER INC. (US) | 1985-04-16 | — | — | US | disclosed |
| US-4351843-A | LOWERING BLOOD GLUCOSE | PFIZER INC. (US) | 1982-09-28 | — | — | US | disclosed |
| US-4282242-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1981-08-04 | — | — | US | disclosed |
| US-4194003-A | New pyrrole derivatives, process for their preparation and therapeutic applications thereof | ALBERT ROLLAND S.A. (FR) | 1980-03-18 | — | — | US | disclosed |