SCHEMBL3695404

SCHEMBL3695404

C=Cc1ccc(OCCOc2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 6/20 0.56
CHRNB4 P30926 4/20 0.56
CHRNA3 P32297 4/20 0.56
CHRNB2 P17787 3/20 0.56
CHRNA4 P43681 3/20 0.56
KCNA3 P22001 1/20 0.54
THRB P10828 1/20 0.53
ALDH1A1 P00352 4/20 0.52
TSHR P16473 1/20 0.52
PKM P14618 1/20 0.50
MAPT P10636 1/20 0.49
KDM4E B2RXH2 1/20 0.49
MEN1 O00255 1/20 0.49
TP53 P04637 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP2D6 P10635 1/20 0.49
HPGD P15428 1/20 0.49
ALOX15 P16050 1/20 0.49
KMT2A Q03164 1/20 0.49
HSD17B10 Q99714 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3562858 0.94 KCNA3 (0.64) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL3241666 0.91 CHRNA7 (0.63) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL28188532 0.85 NPC1 (0.51) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL9831639 0.85 NPC1 (0.61) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL9943360 0.85 CHRNA7 (0.61) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL1260922 0.85 CHRNA7 (0.61) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL6536372 0.84 CHRNA7 (0.46) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL685647 0.83 CHRNA7 (0.46) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL8754087 0.83 CHRNB2 (0.59) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4
SCHEMBL1140632 0.83 CHRNB2 (0.59) CHRNA7CHRNB4CHRNA3CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-55145712-A None JP disclosed
EP-1720063-B1 Resin containing ketene-aldehyde copolymer NIPPON SODA CO (JP) 2010-04-07 EP disclosed
EP-1482361-B1 ACID-DEGRADABLE RESIN COMPOSITIONS CONTAINING KETENE-ALDEHYDE COPOLYMER NIPPON SODA CO (JP) 2007-10-03 EP disclosed
EP-1720063-A1 Resin containing ketene-aldehyde copolymer NIPPON SODA CO., LTD. (JP) 2006-11-08 EP disclosed
US-7105272-B2 Acid-degradable resin compositions containing ketene-aldehyde copolymer NIPPON SODA CO., LTD. (JP) 2006-09-12 US disclosed
US-20050130057-A1 Acid-degradable resin compositions containing ketene-aldehyde copolymer NIPPON SODA CO., LTD. (JP) 2005-06-16 US disclosed
EP-1059314-B1 A resist composition WAKO PURE CHEM IND LTD (JP) 2004-12-22 EP disclosed
EP-1482361-A1 ACID-DEGRADABLE RESIN COMPOSITIONS CONTAINING KETENE-ALDEHYDE COPOLYMER NIPPON SODA CO., LTD. (JP) 2004-12-01 EP disclosed
EP-1059314-A1 A resist composition Wako Pure Chemical Industries, Ltd. (JP) 2000-12-13 EP disclosed
JP-S55145712-A NOVEL HIGH-MOLECULAR COMPOUND HAVING PHASE TRANSFER CATALYTIC EFFECT AND PREPARATION THEREOF AGENCY OF IND SCIENCE & TECHNOL 1980-11-13 JP disclosed