Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CTH | P32929 | 1/20 | 0.36 |
| ▸ | CBS | P35520 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2173720 | 0.82 | TSHR (0.42) | TSHRCTHCBSTHPOTHRB | |
| Hydrochloric Acid SCHEMBL10555403 | 0.80 | THRB (0.44) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL848847 | 0.78 | HDAC6 (0.34) | HDAC6HDAC1HDAC2USP2SMN1; SMN2 | |
| SCHEMBL28061441 | 0.78 | HDAC6 (0.36) | HDAC6HDAC1HDAC2USP2SMN1; SMN2 | |
| SCHEMBL27482952 | 0.78 | DGAT1 (0.33) | HDAC6HDAC1HDAC2ELANEDGAT1 | |
| SCHEMBL9299514 | 0.77 | HDAC6 (0.33) | HDAC6HDAC1HDAC2ELANEDGAT1 | |
| Oxalic Acid SCHEMBL11350983 | 0.77 | TSHR (0.42) | TSHRCTHCBSTHPOTHRB | |
| SCHEMBL1827760 | 0.75 | HDAC6 (0.36) | HDAC6HDAC1HDAC2ELANEDGAT1 | |
| SCHEMBL27804594 | 0.75 | HDAC6 (0.37) | HDAC6HDAC1HDAC2 | |
| SCHEMBL13819665 | 0.74 | HDAC6 (0.34) | HDAC6HDAC1HDAC2USP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113264967-B | Programmed death ligand-1 targeted compound and preparation method and application thereof | 江苏省原子医学研究所 | 2023-04-18 | — | — | CN | claimed |
| CN-111675694-B | Oxime group-containing diaryl pyrimidine HIV-1 reverse transcriptase inhibitor and preparation method and application thereof | 山东大学 | 2021-11-26 | — | — | CN | claimed |
| CN-111592530-B | Acldoxime-containing tacrine derivative selective butyrylcholinesterase inhibitor and preparation method and application thereof | 山东大学 | 2021-09-24 | — | — | CN | claimed |
| CN-113264967-A | Programmed death ligand-1 targeted compound and preparation method and application thereof | 江苏省原子医学研究所 | 2021-08-17 | — | — | CN | claimed |
| CN-112375015-A | Preparation method of di-tert-butyloxycarbonylaminoacetic acid | 安徽昊帆生物有限公司 | 2021-02-19 | — | — | CN | claimed |
| CN-111592530-A | Acldoxime-containing tacrine derivative selective butyrylcholinesterase inhibitor and preparation method and application thereof | 山东大学 | 2020-08-28 | — | — | CN | claimed |
| CN-117024438-A | Esatitecan derivative and application thereof | 杭州爱科瑞思生物医药有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-112375015-B | Preparation method of di-tert-butyloxycarbonyl aminooxy acetic acid | 安徽昊帆生物有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-113264967-B | Programmed death ligand-1 targeted compound and preparation method and application thereof | 江苏省原子医学研究所 | 2023-04-18 | — | — | CN | disclosed |
| CN-111592530-B | Acldoxime-containing tacrine derivative selective butyrylcholinesterase inhibitor and preparation method and application thereof | 山东大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-113264967-A | Programmed death ligand-1 targeted compound and preparation method and application thereof | 江苏省原子医学研究所 | 2021-08-17 | — | — | CN | disclosed |
| CN-112375015-A | Preparation method of di-tert-butyloxycarbonylaminoacetic acid | 安徽昊帆生物有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-112375015-A | Preparation method of di-tert-butyloxycarbonylaminoacetic acid | 安徽昊帆生物有限公司 | 2021-02-19 | — | — | CN | disclosed |
| US-20100291637-A1 | METHOD FOR MODIFYING NUCLEOTIDE CHAIN | PANASONIC CORPORATION (JP) | 2010-11-18 | — | — | US | disclosed |
| EP-1647592-B1 | METHOD OF MODIFYING NUCLEOTIDE CHAIN | PANASONIC CORP (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-20070077629-A1 | Method for modifying nucleotide chain | PANASONIC CORPORATION (JP) | 2007-04-05 | — | — | US | disclosed |
| EP-1647592-A1 | METHOD OF MODIFYING NUCLEOTIDE CHAIN | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2006-04-19 | — | — | EP | disclosed |