Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 4/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL3702662 | 0.86 | ACHE (0.41) | MEN1KMT2AHDAC1THRBHDAC7 | |
| SCHEMBL3704735 | 0.86 | THRB (0.40) | MEN1KMT2AHDAC1THRBHDAC7 | |
| SCHEMBL3702660 | 0.86 | THRB (0.40) | MEN1KMT2AHDAC1THRBHDAC7 | |
| Bicarbonate SCHEMBL3704738 | 0.86 | ACHE (0.41) | MEN1KMT2AHDAC1THRBHDAC7 | |
| SCHEMBL13660768 | 0.86 | THRB (0.40) | MEN1KMT2AHDAC1THRBHDAC7 | |
| SCHEMBL7606170 | 0.86 | MAPT (0.40) | MEN1KMT2AHDAC1THRBHDAC7 | |
| SCHEMBL7602101 | 0.86 | MAPT (0.40) | MEN1KMT2AHDAC1THRBHDAC7 | |
| SCHEMBL12872081 | 0.83 | THRB (0.39) | MEN1KMT2AHDAC1THRBHDAC7 | |
| SCHEMBL12872084 | 0.83 | THRB (0.39) | MEN1KMT2AHDAC1THRBHDAC7 | |
| SCHEMBL12872085 | 0.83 | THRB (0.39) | MEN1KMT2AHDAC1THRBHDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |