SCHEMBL3696268

SCHEMBL3696268

Cc1cc(C)c2c(c1)C(=O)C(O)=C(c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)C2=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA2 P00918 3/20 0.46
▸ ALDH1A1 P00352 3/20 0.46
▸ POLB P06746 2/20 0.46
▸ SMN1; SMN2 Q16637 2/20 0.46
▸ TYR P14679 1/20 0.46
▸ CA1 P00915 2/20 0.43
▸ PTPN1 P18031 1/20 0.43
▸ CYP2C9 P11712 5/20 0.42
▸ CYP2C19 P33261 4/20 0.42
▸ CYP1A2 P05177 3/20 0.42
▸ PTGS1 P23219 4/20 0.39
▸ HIF1A Q16665 3/20 0.38
▸ CYP2D6 P10635 2/20 0.38
▸ HSD17B10 Q99714 2/20 0.38
▸ ELANE P08246 2/20 0.38
▸ MAPT P10636 2/20 0.38
▸ ALOX15 P16050 2/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ PTP4A3 O75365 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3694663 0.94 CA2 (0.46) CA2ALDH1A1POLBSMN1; SMN2TYR
SCHEMBL3753074 0.84 PTPN1 (0.42) CA2ALDH1A1POLBSMN1; SMN2TYR
SCHEMBL3695064 0.82 PTPN1 (0.51) CA2ALDH1A1POLBSMN1; SMN2TYR
SCHEMBL3690041 0.82 PTPN1 (0.42) CA2ALDH1A1POLBSMN1; SMN2TYR
SCHEMBL3688310 0.81 CA2 (0.50) CA2ALDH1A1POLBSMN1; SMN2TYR
SCHEMBL3705368 0.80 CA2 (0.48) CA2ALDH1A1POLBSMN1; SMN2TYR
SCHEMBL3698561 0.80 TDP2 (0.44) CA2ALDH1A1POLBSMN1; SMN2TYR
SCHEMBL3691403 0.79 PTPN1 (0.47) CA2ALDH1A1POLBSMN1; SMN2TYR
SCHEMBL3699283 0.79 PTPN1 (0.47) CA2ALDH1A1POLBSMN1; SMN2TYR
SCHEMBL3699478 0.77 PTPN1 (0.51) CA2ALDH1A1POLBSMN1; SMN2TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8241855-B2 Method for detecting cytosine methylations EPIGENOMICS AG (DE) 2012-08-14 — — US claimed
EP-1325154-B1 METHOD FOR THE DETECTION OF CYTOSINE METHYLATIONS EPIGENOMICS AG (DE) 2007-08-01 — — EP claimed
US-7118868-B2 Method for detecting cytosine methylations EPIGENOMICS AG (DE) 2006-10-10 — — US claimed
EP-1707642-A2 Method for detecting cytosine methylations Epigenomics AG (DE) 2006-10-04 — — EP claimed
EP-1294945-B1 METHOD FOR DETECTING CYTOSINE METHYLATIONS EPIGENOMICS AG (DE) 2006-08-30 — — EP claimed
US-20040152080-A1 Method for detecting cytosine methylations QIAGEN GMBH (DE) 2004-08-05 — — US claimed
EP-1294945-A2 METHOD FOR DETECTING CYTOSINE METHYLATIONS Epigenomics AG (DE) 2003-03-26 — — EP claimed
WO-2001098528-A2 METHOD FOR DETECTING CYTOSINE METHYLATIONS EPIGENOMICS AG (DE) 2001-12-27 — — WO claimed
US-8377638-B2 Process for the detection of cytosine methylations QIAGEN GMBH (DE) 2013-02-19 — — US disclosed
US-8241855-B2 Method for detecting cytosine methylations EPIGENOMICS AG (DE) 2012-08-14 — — US disclosed
US-20100297614-A1 PROCESS FOR THE DETECTION OF CYTOSINE METHYLATIONS QIAGEN GMBH (DE) 2010-11-25 — — US disclosed
EP-1977011-B1 PROCESS FOR THE DETECTION OF CYTOSINE METHYLATIONS QIAGEN GMBH (DE) 2010-07-28 — — EP disclosed
EP-1977011-A1 PROCESS FOR THE DETECTION OF CYTOSINE METHYLATIONS Qiagen GmbH (DE) 2008-10-08 — — EP disclosed
US-20070207472-A1 Method for detecting cytosine methylations QIAGEN GMBH (DE) 2007-09-06 — — US disclosed
US-7118868-B2 Method for detecting cytosine methylations EPIGENOMICS AG (DE) 2006-10-10 — — US disclosed
EP-1707642-A2 Method for detecting cytosine methylations Epigenomics AG (DE) 2006-10-04 — — EP disclosed
EP-1294945-B1 METHOD FOR DETECTING CYTOSINE METHYLATIONS EPIGENOMICS AG (DE) 2006-08-30 — — EP disclosed
US-20040152080-A1 Method for detecting cytosine methylations QIAGEN GMBH (DE) 2004-08-05 — — US disclosed
EP-1294945-A2 METHOD FOR DETECTING CYTOSINE METHYLATIONS Epigenomics AG (DE) 2003-03-26 — — EP disclosed
WO-2001098528-A2 METHOD FOR DETECTING CYTOSINE METHYLATIONS EPIGENOMICS AG (DE) 2001-12-27 — — WO disclosed
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