SCHEMBL369704

SCHEMBL369704

O=C(O)C(=O)c1c[nH]c2ccccc12

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.69
NPC1 O15118 3/20 0.66
RAB9A P51151 3/20 0.66
MEN1 O00255 1/20 0.66
KMT2A Q03164 1/20 0.66
PBRM1 Q86U86 1/20 0.65
ALDH1A1 P00352 1/20 0.65
ATM Q13315 1/20 0.65
GABRA1 P14867 2/20 0.62
GABRG2 P18507 2/20 0.62
GABRB3 P28472 2/20 0.62
GABRA3 P34903 2/20 0.62
GABRA2 P47869 2/20 0.62
GABRB2 P47870 2/20 0.62
GABRP O00591 1/20 0.62
GABRD O14764 1/20 0.62
GABRB1 P18505 1/20 0.62
GABRA5 P31644 1/20 0.62
GABRA4 P48169 1/20 0.62
GABRE P78334 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29465573 1.00 GPR84 (0.69) GPR84NPC1RAB9AMEN1KMT2A
Hydrochloric Acid SCHEMBL6474054 0.98 GPR84 (0.67) GPR84NPC1RAB9AMEN1KMT2A
SCHEMBL4954977 0.90 GPR84 (0.77) GPR84NPC1RAB9AMEN1KMT2A
SCHEMBL64182 0.86 GPR84 (0.77) GPR84NPC1RAB9AMEN1KMT2A
SCHEMBL7890212 0.85 GPR84 (0.69) GPR84NPC1RAB9AMEN1KMT2A
SCHEMBL11140928 0.84 GPR84 (0.59) GPR84NPC1RAB9AMEN1KMT2A
SCHEMBL11140920 0.84 GPR84 (0.59) GPR84NPC1RAB9AMEN1KMT2A
Hydrochloric Acid SCHEMBL7437913 0.84 GPR84 (0.74) GPR84NPC1RAB9AMEN1KMT2A
Hydrochloric Acid SCHEMBL29435427 0.84 GPR84 (0.74) GPR84NPC1RAB9AMEN1KMT2A
SCHEMBL29272694 0.84 GPR84 (0.74) GPR84NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 445 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
EP-4424365-A2 PET FOOD COMPOSITIONS Hill's Pet Nutrition, Inc. (US) 2024-09-04 EP claimed
EP-4017281-B1 PET FOOD COMPOSITIONS HILLS PET NUTRITION INC (US) 2024-08-28 EP claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-116286623-A Metabolic markers for screening young and senescent mesenchymal stem cell-derived exosomes and screening method 中国医学科学院基础医学研究所 2023-06-23 CN claimed
US-11399611-B2 Process for straightening keratin fibres with a heating means and denaturing agents L'OREAL (FR) 2022-08-02 US claimed
CN-114828648-A Pet food compositions 希尔氏宠物营养品公司 2022-07-29 CN claimed
EP-4017281-A1 PET FOOD COMPOSITIONS Hill's Pet Nutrition, Inc. (US) 2022-06-29 EP claimed
WO-2021127701-A1 PET FOOD COMPOSITIONS HILL'S PET NUTRITION, INC. (US) 2021-06-24 WO claimed
CN-109762572-B Preparation method of mercury-polluted soil remediation agent 北京金格玖畅环保科技有限公司 2021-03-23 CN claimed
US-20040204588-A1 Synthesis of indole thiazole compounds as ligands for the Ah receptor WISCONSIN ALUMNI RESEARCH FOUNDATION 2004-10-14 US claimed
EP-1432395-A1 METHOD FOR COLOURING KERATIN FIBRES USING CARBONYL COMPOUNDS TO IMPROVE THE COLOUR STABILITY OF HAIR COLORATION Henkel Kommanditgesellschaft auf Aktien (DE) 2004-06-30 EP claimed
WO-2003068742-A1 SYNTHESIS OF INDOLE THIAZOLE COMPOUNDS AS LIGANDS FOR THE AH RECEPTOR WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2003-08-21 WO claimed
WO-2003030848-A1 METHOD FOR COLOURING KERATIN FIBRES USING CARBONYL COMPOUNDS TO IMPROVE THE COLOUR STABILITY OF HAIR COLORATION HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
WO-2000038632-A1 METHOD FOR DYING KERATIN FIBERS USING 2-OXOCARBOXYLIC ACID DERIVATIVES IN CONJUNCTION WITH NUCLEOPHILES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2000-07-06 WO claimed
EP-0673782-B1 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORP (US) 2000-06-14 EP claimed
EP-0004952-B1 SPIRO-(DIHYDROBENZOFURANPIPERIDINES AND -PYRROLIDINES) AND DERIVATIVES THEREOF, METHODS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM HOECHST AKTIENGESELLSCHAFT (DE) 1982-04-07 EP claimed
EP-0004952-A1 Spiro-(dihydrobenzofuranpiperidines and -pyrrolidines) and derivatives thereof, methods for their preparation and medicines containing them HOECHST AKTIENGESELLSCHAFT (DE) 1979-10-31 EP claimed
US-4166119-A Analgesic and tranquilizing spiro[dihydrobenzofuran]piperidines and pyrrolidines AMERICAN HOECHST CORPORATION (US) 1979-08-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11399611-B2 Process for straightening keratin fibres with a heating means and denaturing agents KRT18, KRTCAP2, TUBB4A GPR84 4450/4885NPC1 4391/4885RAB9A 4079/4885
US-20040204588-A1 Synthesis of indole thiazole compounds as ligands for the Ah receptor AHR, HCAR1, HCAR2 GPR84 102/4885NPC1 2297/4885RAB9A 3841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.