Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3694555 | 0.88 | HTR1A (0.33) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL3697142 | 0.83 | SLC2A1 (0.47) | ALDH1A1 | |
| SCHEMBL3697147 | 0.83 | SLC2A1 (0.47) | ALDH1A1 | |
| SCHEMBL5432710 | 0.82 | SLC2A1 (0.46) | — | |
| SCHEMBL5432717 | 0.82 | SLC2A1 (0.46) | — | |
| SCHEMBL5317247 | 0.80 | MTNR1A (0.36) | SIGMAR1HTR2AHTR2CHTR2BSLC18A3 | |
| SCHEMBL5317252 | 0.80 | MTNR1A (0.36) | SIGMAR1HTR2AHTR2CHTR2BSLC18A3 | |
| SCHEMBL5439676 | 0.78 | KCNH2 (0.36) | SIGMAR1HTR2AHTR2CHTR2BSLC18A3 | |
| SCHEMBL5439683 | 0.78 | KCNH2 (0.36) | SIGMAR1HTR2AHTR2CHTR2BSLC18A3 | |
| SCHEMBL3690604 | 0.78 | SLC2A1 (0.36) | HTR1AADRA1DADRA1AADRA1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2239260-A1 | Novel compounds with antibacterial activity | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2010-10-13 | — | — | EP | disclosed |