Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27955728 | 1.00 | ACHE (0.48) | ACHEALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL17737832 | 0.85 | ACHE (0.68) | ACHEALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL8208247 | 0.85 | ACHE (0.68) | ACHEALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL22051903 | 0.83 | ACHE (0.48) | ACHEALDH1A1SMN1; SMN2MAPTPOLB | |
| SCHEMBL22050356 | 0.82 | MEN1 (0.57) | ACHEALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL223522 | 0.82 | MEN1 (0.57) | ACHEALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL4950926 | 0.82 | ALDH1A1 (0.44) | ACHEALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL3694310 | 0.81 | ALDH1A1 (0.43) | ACHEALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL22050365 | 0.80 | ACHE (0.42) | ACHEALDH1A1SMN1; SMN2TSHRMAPT | |
| SCHEMBL3696722 | 0.79 | ESR1 (0.46) | ACHEALDH1A1SMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741240-B2 | Transition metal compounds for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-06-22 | — | — | US | claimed |
| EP-1753773-A1 | TRANSITION METAL COMPOUNDS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | ExxonMobil Chemical Patents Inc. (US) | 2007-02-21 | — | — | EP | claimed |
| WO-2005118605-A1 | TRANSITION METAL COMPOUNDS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS, INC. (US) | 2005-12-15 | — | — | WO | claimed |