Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 11/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5254100 | 0.88 | KCNH2 (0.36) | SLC2A1SIGMAR1KCNH2ABCB1 | |
| SCHEMBL5651029 | 0.86 | SLC2A1 (0.53) | SLC2A1KCNH2 | |
| SCHEMBL3686883 | 0.85 | KCNH2 (0.34) | SLC2A1SIGMAR1KCNH2 | |
| SCHEMBL3695685 | 0.78 | DRD4 (0.30) | — | |
| SCHEMBL5262026 | 0.77 | KCNH2 (0.32) | KCNH2 | |
| SCHEMBL3690918 | 0.76 | BCHE (0.32) | MEN1KMT2A | |
| SCHEMBL5255791 | 0.73 | KCNH2 (0.52) | SLC2A1KCNH2MEN1KMT2A | |
| SCHEMBL3694994 | 0.72 | — | — | |
| SCHEMBL5254382 | 0.72 | KCNH2 (0.51) | SLC2A1KCNH2 | |
| SCHEMBL3775157 | 0.71 | KCNH2 (0.41) | SLC2A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2239260-A1 | Novel compounds with antibacterial activity | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2010-10-13 | — | — | EP | disclosed |