Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 9/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5255791 | 0.90 | KCNH2 (0.52) | KCNH2SLC2A1 | |
| SCHEMBL3784362 | 0.90 | KCNH2 (0.35) | KCNH2SLC2A1 | |
| SCHEMBL3784584 | 0.90 | KCNH2 (0.35) | KCNH2SLC2A1 | |
| SCHEMBL5317187 | 0.90 | KCNH2 (0.32) | KCNH2SLC2A1MTNR1AMTNR1B | |
| SCHEMBL5650870 | 0.86 | KCNH2 (0.49) | KCNH2SLC2A1 | |
| SCHEMBL5942923 | 0.86 | SLC2A1 (0.33) | KCNH2SLC2A1 | |
| SCHEMBL5943183 | 0.86 | SLC2A1 (0.33) | KCNH2SLC2A1 | |
| SCHEMBL3775467 | 0.86 | KCNH2 (0.33) | KCNH2SLC2A1 | |
| SCHEMBL5254100 | 0.83 | KCNH2 (0.36) | KCNH2SLC2A1 | |
| SCHEMBL3686883 | 0.80 | KCNH2 (0.34) | KCNH2SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324030-A1 | 5-Quinoline derivatives having an anti-bacterial activity | MORPHOCHEM AKTIENGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE (DE) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324030-A1 | 5-Quinoline derivatives having an anti-bacterial activity | TOP2A, TOP1, TOP2B | KCNH2 3216/4885SLC2A1 4605/4885CCR3 4714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.