Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12743336 | 0.92 | HDAC6 (0.41) | HDAC6HDAC1HDAC2ELANECTSK | |
| SCHEMBL883432 | 0.92 | HDAC6 (0.41) | HDAC6HDAC1HDAC2ELANECTSK | |
| SCHEMBL3139219 | 0.92 | HDAC6 (0.41) | HDAC6HDAC1HDAC2ELANECTSK | |
| SCHEMBL789539 | 0.84 | HDAC6 (0.37) | HDAC6HDAC1HDAC2ELANECTSK | |
| SCHEMBL16594410 | 0.84 | HDAC6 (0.37) | HDAC6HDAC1HDAC2ELANECTSK | |
| SCHEMBL6016032 | 0.82 | HDAC6 (0.41) | HDAC6HDAC1HDAC2ELANECTSK | |
| SCHEMBL6016036 | 0.82 | HDAC6 (0.41) | HDAC6HDAC1HDAC2ELANECTSK | |
| SCHEMBL16327287 | 0.79 | CTSK (0.34) | HDAC6HDAC1HDAC2CTSK | |
| Hydrogen Peroxide SCHEMBL28399931 | 0.78 | SMN1; SMN2 (0.40) | HDAC6HDAC1HDAC2ELANE | |
| SCHEMBL11896861 | 0.78 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637561-B2 | Linked diimidazole derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2014-01-28 | — | — | US | disclosed |
| WO-2010096462-A1 | LINKED DIIMIDAZOLE DERIVATIVES | ENANTA PHARMACEUTICALS, INC (US) | 2010-08-26 | — | — | WO | disclosed |