SCHEMBL3698233

SCHEMBL3698233

Cc1cccc(N(c2cccc(C)c2)S(=O)(=O)c2cccc3ccccc23)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
HTR2A P28223 2/20 0.44
HTR2C P28335 2/20 0.44
HTR6 P50406 2/20 0.44
HTR1A P08908 1/20 0.44
HTR7 P34969 1/20 0.44
DRD3 P35462 1/20 0.44
SIGMAR1 Q99720 1/20 0.43
KEAP1 Q14145 1/20 0.42
NFE2L2 Q16236 1/20 0.42
HCRTR1 O43613 1/20 0.41
PRSS1 P07477 3/20 0.41
GLA P06280 2/20 0.41
PKM P14618 1/20 0.41
C1R P00736 1/20 0.41
KDM4E B2RXH2 2/20 0.40
MAPT P10636 2/20 0.40
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3698727 0.84 CA9 (0.47) CA1CA2CA9HTR2AHTR2C
SCHEMBL3703471 0.84 CA1 (0.53) CA1CA2CA9HTR2AHTR2C
SCHEMBL3711033 0.83 PKM (0.47) HTR2AHTR2CGLAPKMMAPT
SCHEMBL4507193 0.83 CA1 (0.41) CA1CA2CA9SIGMAR1GLA
SCHEMBL3248145 0.73 CA1 (0.57) CA1CA2CA9HTR2AHTR2C
SCHEMBL18537467 0.73 CA1 (0.57) CA1CA2CA9HTR2AHTR2C
SCHEMBL259694 0.73 MAPT (0.60) HTR6HCRTR1MAPTMEN1LMNA
SCHEMBL3700907 0.72 CA12 (0.54) CA9PKMMAPTLMNAHTT
Hydrochloric Acid SCHEMBL28348315 0.72 HTR2A (0.55) CA1CA2CA9HTR2AHTR2C
SCHEMBL2371944 0.70 HTR2A (0.57) CA1CA2CA9HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120118616-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, POLYIMIDE RESIN FILM USING SAME, AND FLEXIBLE PRINTED CIRCUIT BOARD SUMITOMO ELECTRIC PRINTED CIRCUITS, INC. (JP) 2012-05-17 US disclosed