SCHEMBL3700907

SCHEMBL3700907

Cc1ccc(S(=O)(=O)N(c2cccc(C)c2)c2cccc(C)c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.54
CA9 Q16790 1/20 0.54
LMNA P02545 1/20 0.52
C5AR1 P21730 1/20 0.51
ALDH1A1 P00352 4/20 0.51
MAPT P10636 2/20 0.50
PKM P14618 2/20 0.50
MCOLN3 Q8TDD5 1/20 0.50
NPSR1 Q6W5P4 3/20 0.49
ESR1 P03372 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
HPGD P15428 1/20 0.47
CYP2C19 P33261 1/20 0.47
HSD17B10 Q99714 1/20 0.47
HTT P42858 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
MAPK1 P28482 1/20 0.46
TP53 P04637 1/20 0.46
TDP1 Q9NUW8 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3697451 0.83 PKM (0.71) CA12CA9C5AR1ALDH1A1MAPT
SCHEMBL3701001 0.81 MAPT (0.67) CA12CA9LMNAC5AR1ALDH1A1
SCHEMBL28447555 0.79 KDM4E (0.57) CA12CA9LMNAC5AR1ALDH1A1
SCHEMBL28634601 0.78 ALDH1A1 (0.66) CA12CA9C5AR1ALDH1A1MAPT
SCHEMBL28380035 0.78 NPSR1 (0.69) CA12CA9LMNAC5AR1ALDH1A1
SCHEMBL6324948 0.78 LMNA (0.63) CA12CA9LMNAC5AR1ALDH1A1
SCHEMBL3711033 0.76 PKM (0.47) LMNAALDH1A1MAPTPKMCYP3A4
SCHEMBL3702995 0.76 ALDH1A1 (0.63) CA12CA9C5AR1ALDH1A1MAPT
SCHEMBL3886338 0.75 ALDH1A1 (0.62) CA12CA9C5AR1ALDH1A1MAPT
SCHEMBL10212263 0.74 CA12 (0.67) CA12CA9LMNAC5AR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120118616-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, POLYIMIDE RESIN FILM USING SAME, AND FLEXIBLE PRINTED CIRCUIT BOARD SUMITOMO ELECTRIC PRINTED CIRCUITS, INC. (JP) 2012-05-17 US disclosed