SCHEMBL3711033

SCHEMBL3711033

Cc1cccc(N(c2cccc(C)c2)S(=O)(=O)c2ccccc2C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.47
GLA P06280 3/20 0.44
ALDH1A1 P00352 2/20 0.41
HCRTR2 O43614 1/20 0.41
LMNA P02545 3/20 0.40
RECQL P46063 1/20 0.40
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
HPGD P15428 1/20 0.39
CYP2C19 P33261 1/20 0.39
HSD17B10 Q99714 1/20 0.39
POLB P06746 2/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 1/20 0.38
HSD11B1 P28845 1/20 0.38
HTT P42858 1/20 0.38
TP53 P04637 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3706061 0.84 PKM (0.50) PKMALDH1A1HCRTR2RECQLHTR2A
SCHEMBL3698233 0.83 CA1 (0.45) PKMGLAALDH1A1LMNAHTR2A
SCHEMBL3694048 0.81 HCRTR2 (0.54) PKMALDH1A1HCRTR2HTR2AHTR2C
SCHEMBL8351582 0.76 PKM (0.46) PKMGLAALDH1A1RECQLPOLB
SCHEMBL3700907 0.76 CA12 (0.54) PKMALDH1A1LMNACYP3A4CYP2C9
SCHEMBL4507193 0.72 CA1 (0.41) PKMGLAALDH1A1LMNACYP3A4
SCHEMBL3822613 0.72 MCOLN3 (0.60) PKMGLAALDH1A1HTR2AHTR2C
Hydrochloric Acid SCHEMBL5808143 0.70 MCOLN3 (0.58) PKMGLAALDH1A1HTR2AHTR2C
SCHEMBL701463 0.70 ALDH1A1 (0.55) ALDH1A1HCRTR2LMNAHTR2AHTR2C
SCHEMBL9683412 0.69 MCOLN3 (0.49) PKMGLAALDH1A1HCRTR2HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120118616-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, POLYIMIDE RESIN FILM USING SAME, AND FLEXIBLE PRINTED CIRCUIT BOARD SUMITOMO ELECTRIC PRINTED CIRCUITS, INC. (JP) 2012-05-17 US disclosed