Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | FASN | P49327 | 7/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289051 | 0.80 | RXFP1 (0.39) | LRRK2KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL289980 | 0.80 | LCK (0.39) | KMT2AMEN1ALDH1A1HPGDNPC1 | |
| SCHEMBL6720921 | 0.79 | LRRK2 (0.46) | LRRK2KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL289298 | 0.77 | MAPT (0.43) | KMT2AMEN1ALDH1A1HPGDRXFP1 | |
| SCHEMBL31560030 | 0.76 | RXFP1 (0.38) | LRRK2KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL298875 | 0.76 | KMT2A (0.40) | LRRK2KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL29360338 | 0.76 | KMT2A (0.40) | LRRK2KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL3779636 | 0.76 | RXFP1 (0.38) | LRRK2KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL21504320 | 0.75 | RXFP1 (0.37) | LRRK2KMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL290192 | 0.74 | RXFP1 (0.36) | LRRK2KMT2AMEN1FASNCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427427-B1 | 4-CYANO-3-BENZOYLAMINO-N-PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | SYNGENTA PARTICIPATIONS AG (CH) | 2013-12-25 | — | — | EP | disclosed |
| WO-2013092942-A1 | USE OF AMINOBENZAMIDE DERIVATIVES FOR CONTROLLING ANIMAL PARASITES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-06-27 | — | — | WO | disclosed |
| US-8431514-B2 | 4-cyano-3-benzoylamino-N-phenyl-benzamides for use in pest control | SYNGENTA CROP PROTECTION LLC (US) | 2013-04-30 | — | — | US | disclosed |
| US-20120122975-A1 | 4-CYANO-3-BENZOYLAMINO-N-PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | SYNGENTA CROP PROTECTION LLC (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122975-A1 | 4-CYANO-3-BENZOYLAMINO-N-PHENYL-BENZAMIDES FOR USE IN PEST CONTROL | NISCH, AADAC, ACHE | LRRK2 2121/4885KMT2A 901/4885MEN1 4616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.