SCHEMBL298875

SCHEMBL298875

Cc1cc(C#N)ccc1C(=O)Nc1cc(C(=O)Nc2c(Cl)cc(C(F)(C(F)(F)F)C(F)(F)F)cc2Cl)ccc1C#N

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.40
MEN1 O00255 4/20 0.40
PDK1 Q15118 1/20 0.39
PDK2 Q15119 1/20 0.39
PDK3 Q15120 1/20 0.39
PDK4 Q16654 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
RXFP1 Q9HBX9 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
NR1H4 Q96RI1 1/20 0.37
LRRK2 Q5S007 1/20 0.37
ALDH1A1 P00352 5/20 0.36
HPGD P15428 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 2/20 0.36
KDM4E B2RXH2 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29360338 1.00 KMT2A (0.40) KMT2AMEN1PDK1PDK2PDK3
SCHEMBL29360734 0.96 KMT2A (0.39) KMT2AMEN1PDK1PDK2PDK3
SCHEMBL3703139 0.96 KMT2A (0.39) KMT2AMEN1PDK1PDK2PDK3
SCHEMBL28581106 0.95 MEN1 (0.37) KMT2AMEN1PDK1PDK2PDK3
SCHEMBL29427425 0.94 KMT2A (0.38) KMT2AMEN1PDK1PDK2PDK3
SCHEMBL297991 0.94 KMT2A (0.38) KMT2AMEN1PDK1PDK2PDK3
SCHEMBL3700196 0.92 KMT2A (0.38) KMT2AMEN1PDK1PDK2PDK3
SCHEMBL29362569 0.92 KMT2A (0.38) KMT2AMEN1PDK1PDK2PDK3
SCHEMBL29362173 0.90 KMT2A (0.36) KMT2AMEN1PDK1PDK2PDK3
SCHEMBL3699644 0.90 KMT2A (0.36) KMT2AMEN1PDK1PDK2PDK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 529 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250338849-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2025-11-06 US claimed
US-20240225002-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI INDUSTRIES LTD. (IN) 2024-07-11 US claimed
CN-117396074-A Fungicidal compositions containing oxadiazole compounds PI工业有限公司 2024-01-12 CN claimed
US-11839214-B2 Fungicidal mixture comprising substituted pyridines BASF SE (DE) 2023-12-12 US claimed
CN-116076518-A Pyrimidinium compounds and mixtures thereof for combating animal pests 巴斯夫欧洲公司 2023-05-09 CN claimed
EP-3978504-A1 CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDINE DERIVATIVES FOR COMBATING ANIMAL PESTS BASF SE (DE) 2022-04-06 EP claimed
US-20220046925-A1 METHOD OF CONTROLLING PESTS BY SEED TREATMENT APPLICATION OF A MESOIONIC COMPOUND OR MIXTURE THEREOF BASF SE (DE) 2022-02-17 US claimed
EP-3942933-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF Agrochemical Products B.V. (NL) 2022-01-26 EP claimed
CN-108289456-B Mixture of cis-jasmone and bacillus amyloliquefaciens 巴斯夫欧洲公司 2022-01-11 CN claimed
EP-3601298-B1 PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2021-12-01 EP claimed
US-20160227772-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF AGROCHEMICAL PRODUCTS B.V. (NL) 2016-08-11 US claimed
WO-2016059240-A1 METHOD AND PESTICIDAL MIXTURES FOR CONTROLLING PENTATOMIDAE PESTS BASF SE (DE) 2016-04-21 WO claimed
WO-2015055755-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF SE (DE) 2015-04-23 WO claimed
WO-2015055752-A1 INSECTICIDAL ACTIVE MIXTURES COMPRISING CARBOXAMIDE COMPOUND BASF SE (DE) 2015-04-23 WO claimed
WO-2015055757-A1 USE OF PESTICIDAL ACTIVE CARBOXAMIDE DERIVATIVE IN SOIL AND SEED APPLICATION AND TREATMENT METHODS BASF SE (DE) 2015-04-23 WO claimed
EP-2427427-B1 4-CYANO-3-BENZOYLAMINO-N-PHENYL-BENZAMIDES FOR USE IN PEST CONTROL SYNGENTA PARTICIPATIONS AG (CH) 2013-12-25 EP claimed
US-8431514-B2 4-cyano-3-benzoylamino-N-phenyl-benzamides for use in pest control SYNGENTA CROP PROTECTION LLC (US) 2013-04-30 US claimed
US-20120122975-A1 4-CYANO-3-BENZOYLAMINO-N-PHENYL-BENZAMIDES FOR USE IN PEST CONTROL SYNGENTA CROP PROTECTION LLC (US) 2012-05-17 US claimed
EP-2427427-A1 4 -CYANO- 3 -BENZOYLAMINO-N- PHENYL-BENZAMIDES FOR USE IN PEST CONTROL Syngenta Participations AG (CH) 2012-03-14 EP claimed
WO-2010127926-A1 4 -CYANO- 3 -BENZOYLAMINO-N- PHENYL-BENZAMIDES FOR USE IN PEST CONTROL SYNGENTA PARTICIPATIONS AG (CH) 2010-11-11 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839214-B2 Fungicidal mixture comprising substituted pyridines ME1, DPM1, TH KMT2A 2611/4885MEN1 1988/4885PDK1 3098/4885
US-20160227772-A1 AGRICULTURAL MIXTURES COMPRISING CARBOXAMIDE COMPOUND NAAA, AADAC, PYCARD KMT2A 855/4885MEN1 991/4885PDK1 4183/4885
US-20250338849-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES ME1, DPM1, ERG28 KMT2A 2692/4885MEN1 1734/4885PDK1 3003/4885
US-20240225002-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS OXA1L, NOX1, NOX3 KMT2A 3280/4885MEN1 2968/4885PDK1 2958/4885
US-20220046925-A1 METHOD OF CONTROLLING PESTS BY SEED TREATMENT APPLICATION OF A MESOIONIC COMPOUND OR MIXTURE THEREOF MANBA, CMA1, MTX1 KMT2A 2080/4885MEN1 157/4885PDK1 3863/4885
US-20120122975-A1 4-CYANO-3-BENZOYLAMINO-N-PHENYL-BENZAMIDES FOR USE IN PEST CONTROL NISCH, AADAC, ACHE KMT2A 901/4885MEN1 4616/4885PDK1 3682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.