Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16390544 | 0.85 | NPC1 (0.36) | ALDH1A1MAPTL3MBTL1RAB9ACYP1A2 | |
| Hydrochloric Acid SCHEMBL3703679 | 0.83 | AR (0.33) | ALDH1A1MAPTTP53AR | |
| Hydrochloric Acid SCHEMBL16177155 | 0.83 | ALDH1A1 (0.39) | ALDH1A1MAPTHPGDKDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL3698492 | 0.80 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDKDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL16177156 | 0.78 | ALDH1A1 (0.37) | ALDH1A1MAPTHPGDKDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL15612707 | 0.78 | HPGD (0.33) | ALDH1A1MAPTHPGDKDM4EHSD17B10 | |
| SCHEMBL3698490 | 0.77 | ALDH1A1 (0.38) | ALDH1A1MAPTHPGDKDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL16390253 | 0.76 | HPGD (0.36) | ALDH1A1MAPTHPGDKDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL3670743 | 0.75 | CRHR1 (0.33) | ALDH1A1MAPTL3MBTL1RAB9AMEN1 | |
| SCHEMBL16086160 | 0.74 | ALDH1A1 (0.36) | ALDH1A1MAPTHPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2070964-B9 | PROCESS FOR PRODUCTION OF HYDROGENATED POLYMERS AND HYDROGENATED POLYMERS | KURARAY CO (JP) | 2012-10-31 | — | — | EP | disclosed |
| EP-2070964-B1 | PROCESS FOR PRODUCTION OF HYDROGENATED POLYMERS AND HYDROGENATED POLYMERS | KURARAY CO (JP) | 2012-05-16 | — | — | EP | disclosed |
| EP-2070964-A1 | PROCESS FOR PRODUCTION OF HYDROGENATED POLYMERS AND HYDROGENATED POLYMERS | Kuraray Co., Ltd. (JP) | 2009-06-17 | — | — | EP | disclosed |