⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684858 | 0.74 | TDP1 (0.39) | — | |
| SCHEMBL2059980 | 0.74 | — | — | |
| SCHEMBL27485700 | 0.73 | — | — | |
| SCHEMBL6461409 | 0.73 | — | — | |
| SCHEMBL5492471 | 0.73 | — | — | |
| SCHEMBL6429062 | 0.72 | ALDH1A1 (0.42) | — | |
| SCHEMBL6471705 | 0.71 | LMNA (0.39) | — | |
| SCHEMBL476333 | 0.70 | ERN1 (0.39) | — | |
| SCHEMBL27843652 | 0.70 | ERN1 (0.39) | — | |
| SCHEMBL9375433 | 0.70 | TDP1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460789-B1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2017-04-19 | — | — | EP | disclosed |
| US-9079830-B2 | Method for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-07-14 | — | — | US | disclosed |
| EP-2460789-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2012-06-06 | — | — | EP | disclosed |
| US-20120123154-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-05-17 | — | — | US | disclosed |
| US-6664297-B1 | Impeding formation of amyloid fibers or dissolving existing fibers in mammals | UNIVERSIDADE FEDERAL DO RIO DE JANEIRO (BR) | 2003-12-16 | — | — | US | disclosed |
| WO-2001028546-A1 | INHIBITION OF AMYLOIDOSES BY USING AROMATIC OR HETEROAROMATIC COMPOUNDS SUBSTITUTED BY ELECTRON-WITHDRAWING GROUPS | UNIVERSIDADE FEDERAL DO RIO DE JANEIRO (BR) | 2001-04-26 | — | — | WO | disclosed |