Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31696762 | 0.74 | ALDH1A1 (0.36) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL30307422 | 0.70 | ALDH1A1 (0.42) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL370014 | 0.70 | CHEK1 (0.38) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL64923 | 0.70 | ALDH1A1 (0.42) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL27977196 | 0.68 | IMPDH2 (0.46) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL17620565 | 0.67 | KDM4E (0.53) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL21622668 | 0.66 | KDM4E (0.34) | KDM4EL3MBTL1ATM | |
| SCHEMBL21886150 | 0.66 | KDM4E (0.43) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL20980503 | 0.65 | MAPT (0.42) | KDM4EALDH1A1GAAGLAHPGD | |
| SCHEMBL19229400 | 0.64 | KDM4E (0.37) | KDM4EALDH1A1GAAGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |