Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 1.00 |
| ▸ | MIF | P14174 | 5/20 | 1.00 |
| ▸ | MAOA | P21397 | 4/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.76 |
| ▸ | TNF | P01375 | 2/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | ACHE | P22303 | 3/20 | 0.67 |
| ▸ | BCHE | P06276 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.66 |
| ▸ | STK17B | O94768 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3694617 | 1.00 | MAOB (1.00) | MAOBMIFMAOACYP19A1TNF | |
| SCHEMBL30462578 | 1.00 | MAOB (1.00) | MAOBMIFMAOACYP19A1TNF | |
| SCHEMBL30462577 | 1.00 | MAOB (1.00) | MAOBMIFMAOACYP19A1TNF | |
| SCHEMBL30977980 | 1.00 | MAOB (1.00) | MAOBMIFMAOACYP19A1TNF | |
| SCHEMBL2981650 | 1.00 | MAOB (1.00) | MAOBMIFMAOACYP19A1TNF | |
| SCHEMBL14033556 | 0.89 | MIF (0.81) | MAOBMIFMAOACYP19A1TNF | |
| SCHEMBL27560521 | 0.88 | MAOB (0.86) | MAOBMIFMAOACYP19A1TNF | |
| SCHEMBL6967940 | 0.86 | MAOB (0.76) | MAOBMIFMAOACYP19A1TNF | |
| SCHEMBL7701204 | 0.86 | MIF (1.00) | MAOBMIFMAOACYP19A1TNF | |
| SCHEMBL15489882 | 0.86 | MAOB (0.76) | MAOBMIFMAOACYP19A1TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166274-B2 | Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds | L'OREAL (FR) | 2007-01-23 | — | — | US | claimed |
| US-20040047820-A1 | Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds | SOCIETE L'OREAL S.A. (FR) | 2004-03-11 | — | — | US | claimed |
| US-6627180-B2 | Particles having protection factor UV-APPD and an amino substituted 2-hydroxybenzophenone | SOCIETE L'OREAL S.A. (FR) | 2003-09-30 | — | — | US | claimed |
| US-20030152532-A1 | SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS | SOCIETE L'OREAL S.A. (FR) | 2003-08-14 | — | — | US | claimed |
| CN-107847414-B | Composition comprising a UV screening agent, an anionically crosslinked hydrophilic polymer, a surfactant having an HLB less than or equal to 5, and a siloxane copolymer | 欧莱雅 | 2021-09-10 | — | — | CN | disclosed |
| EP-2872107-B1 | COSMETIC COMPOSITION CONTAINING SCREENING COMPOSITE PARTICLES | OREAL (FR) | 2021-07-21 | — | — | EP | disclosed |
| CN-111343968-A | Composition comprising at least one acrylic polymer and at least one insoluble organic masking agent | 莱雅公司 | 2020-06-26 | — | — | CN | disclosed |
| US-9682919-B2 | Small molecule inhibitors of Dusp6 and uses therefor | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2017-06-20 | — | — | US | disclosed |
| US-20160355459-A1 | Small Molecule Inhibitors of Dusp6 and Uses Therefor | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2016-12-08 | — | — | US | disclosed |
| US-9439877-B2 | Small molecule inhibitors of Dusp6 and uses therefor | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2016-09-13 | — | — | US | disclosed |
| US-20160113889-A1 | Small Molecule Inhibitors of Dusp6 and Uses Therefor | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2016-04-28 | — | — | US | disclosed |
| US-9127016-B2 | Small molecule inhibitors of Dusp6 and uses therefor | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2015-09-08 | — | — | US | disclosed |
| WO-1999065495-A1 | INHIBITORS OF TRANSCRIPTION FACTOR NF-λB | SMITHKLINE BEECHAM CORPORATION (US) | 1999-12-23 | — | — | WO | disclosed |
| EP-0015156-A1 | Basically-substituted tricyclic pyrazoles, their preparation and their use as antiinflammatory agents | E.R. Squibb & Sons, Inc. (US) | 1980-09-03 | — | — | EP | disclosed |
| US-4173634-A | Basically-substituted tricyclic pyrazoles useful as antiinflammatory agents | E. R. SQUIBB & SONS, INC. (US) | 1979-11-06 | — | — | US | disclosed |
| US-4053514-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1977-10-11 | — | — | US | disclosed |
| US-4038274-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1977-07-26 | — | — | US | disclosed |
| US-3995052-A | Indenopyran- and indenothiopyranalkylamines III in the treatment of depression | AYERST MCKENNA AND HARRISON LTD. (CA) | 1976-11-30 | — | — | US | disclosed |
| US-3983288-A | Fibers and fabrics containing optical brightening agents | EASTMAN KODAK COMPANY (US) | 1976-09-28 | — | — | US | disclosed |
| US-3969527-A | INDENO(1,2-C)PYRAZOLE | E. R. SQUIBB & SONS, INC. (US) | 1976-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160113889-A1 | Small Molecule Inhibitors of Dusp6 and Uses Therefor | DUSP26, DUSP6, DUSP2 | MAOB 4129/4885MIF 161/4885MAOA 4194/4885 |
| US-20040047820-A1 | Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds | SUCLG1, CUTA, DLD | MAOB 1776/4885MIF 3072/4885MAOA 2132/4885 |
| US-20160355459-A1 | Small Molecule Inhibitors of Dusp6 and Uses Therefor | DUSP26, DUSP6, DUSP2 | MAOB 4129/4885MIF 161/4885MAOA 4194/4885 |
| US-20030152532-A1 | SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS | HADHB, SDHA, ERCC4 | MAOB 1274/4885MIF 2357/4885MAOA 1696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.