Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 6/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6253306 | 0.73 | AHR (0.39) | PNMT | |
| SCHEMBL8612336 | 0.70 | PNMT (0.39) | PNMTDRD2DRD3CA12CA9 | |
| SCHEMBL11017385 | 0.69 | TRPA1 (0.44) | PNMTDRD2DRD3TRPA1CYP11B1 | |
| SCHEMBL4967364 | 0.68 | DRD2 (0.47) | PNMTDRD2DRD3CA12CA9 | |
| SCHEMBL3523194 | 0.66 | PNMT (0.41) | PNMTDRD2DRD3CA12CA9 | |
| SCHEMBL3492241 | 0.66 | PRKCI (0.47) | PNMTDRD2DRD3 | |
| SCHEMBL7038650 | 0.66 | TRPA1 (0.44) | PNMTDRD2DRD3TRPA1CYP11B1 | |
| SCHEMBL28664612 | 0.64 | CA12 (0.46) | CA12CA9CYP2A6USP2TRPA1 | |
| SCHEMBL1786744 | 0.63 | PNMT (0.50) | PNMTDRD2DRD3CA12CA9 | |
| SCHEMBL28482571 | 0.63 | PNMT (0.42) | PNMTDRD2DRD3CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2748157-A1 | METHOD FOR PRODUCING TETRAZOLE-SUBSTITUTED ANTHRANILIC ACID DIAMIDE DERIVATIVES BY REACTING BENZOXAZINONES WITH AMINES | Bayer Intellectual Property GmbH (DE) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013030100-A1 | METHOD FOR PRODUCING TETRAZOLE-SUBSTITUTED ANTHRANILIC ACID DIAMIDE DERIVATIVES BY REACTING BENZOXAZINONES WITH AMINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-03-07 | — | — | WO | disclosed |
| EP-2203459-A1 | SPIROCYCLIC AMINOQUINOLONES AS GSK-3 INHIBITORS | Activx Biosciences, Inc. (US) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009035684-A1 | SPIROCYCLIC AMINOQUINOLONES AS GSK-3 INHIBITORS | ACTIVX BIOSCIENCES, INC. (US) | 2009-03-19 | — | — | WO | disclosed |