Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9630416 | 0.97 | POLB (0.32) | POLBALDH1A1MAPTCYP1A2CYP2A6 | |
| SCHEMBL28108415 | 0.80 | POLB (0.52) | POLBALDH1A1MAPTTSHRNOS3 | |
| SCHEMBL10988740 | 0.78 | GAA (0.34) | POLBALDH1A1MAPT | |
| SCHEMBL10983765 | 0.78 | GAA (0.34) | POLBALDH1A1MAPT | |
| SCHEMBL1335872 | 0.78 | KMT2A (0.44) | POLBALDH1A1MAPTCYP1A2CYP2A6 | |
| SCHEMBL30951592 | 0.77 | KEAP1 (0.52) | ALDH1A1MAPTCYP1A2TSHRKEAP1 | |
| SCHEMBL1143602 | 0.77 | KEAP1 (0.52) | ALDH1A1MAPTCYP1A2TSHRKEAP1 | |
| SCHEMBL27681489 | 0.77 | METAP2 (0.41) | ALDH1A1MAPTCYP1A2METAP2 | |
| SCHEMBL18461006 | 0.76 | IDO1 (0.33) | POLBALDH1A1MAPTCYP1A2CYP2A6 | |
| SCHEMBL10981989 | 0.75 | MAPT (0.42) | POLBALDH1A1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611918-B | Dibenzofurane-based binary-axis chiral organic circularly polarized phosphorescent compounds | 哈尔滨工业大学（深圳） | 2024-01-02 | — | — | CN | claimed |
| CN-113121382-A | Metal compound material and preparation method thereof, quantum dot light-emitting diode and light-emitting device | TCL集团股份有限公司 | 2021-07-16 | — | — | CN | claimed |
| WO-2025020886-A1 | AZAQUINAZOLINE RING DERIVATIVE AND USE THEREOF | 浙江星浩澎博医药有限公司 | 2025-01-30 | — | — | WO | disclosed |
| CN-115611918-B | Dibenzofurane-based binary-axis chiral organic circularly polarized phosphorescent compounds | 哈尔滨工业大学（深圳） | 2024-01-02 | — | — | CN | disclosed |
| CN-113121382-B | Metal compound material and preparation method thereof, quantum dot light emitting diode and light emitting device | TCL科技集团股份有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-113680386-B | N-heterocyclic carbene-squaraine difunctional catalyst and preparation method thereof | 深圳湾实验室坪山生物医药研发转化中心 | 2023-08-11 | — | — | CN | disclosed |
| CN-113731488-B | N-heterocyclic carbene-urea difunctional catalyst and preparation method thereof | 深圳湾实验室坪山生物医药研发转化中心 | 2023-08-04 | — | — | CN | disclosed |
| CN-113680385-B | N-heterocyclic carbene-thiourea bifunctional group catalyst and preparation method and application thereof | 深圳湾实验室坪山生物医药研发转化中心 | 2023-05-23 | — | — | CN | disclosed |
| WO-2023023881-A1 | N-HETEROCYCLIC CARBENE-THIOUREA BIFUNCTIONAL GROUP CATALYST AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳湾实验室坪山生物医药研发转化中心 | 2023-03-02 | — | — | WO | disclosed |
| WO-2023023882-A1 | NITROGEN HETEROCYCLIC CARBENE-SQUARIC AMIDE BIFUNCTIONAL CATALYST AND PREPARATION METHOD THEREFOR | 深圳湾实验室坪山生物医药研发转化中心 | 2023-03-02 | — | — | WO | disclosed |
| WO-2023023880-A1 | NITROGEN HETEROCYCLIC CARBENE-UREA BIFUNCTIONAL CATALYST AND PREPARATION METHOD THEREFOR | 深圳湾实验室坪山生物医药研发转化中心 | 2023-03-02 | — | — | WO | disclosed |
| EP-2197552-B1 | NOVEL TETRAHYDROFUSEDPYRIDINES AS HISTONE DEACETYLASE INHIBITORS | 4SC AG (DE) | 2012-11-21 | — | — | EP | disclosed |
| EP-2197552-A2 | NOVEL TETRAHYDROFUSEDPYRIDINES AS HISTONE DEACETYLASE INHIBITORS | 4SC AG (DE) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009037001-A2 | NOVEL TETRAHYDROFUSEDPYRIDINES AS HISTONE DEACETYLASE INHIBITORS | 4SC AG (DE) | 2009-03-26 | — | — | WO | disclosed |
| US-6218397-B1 | FOR THERAPY OF STRESS-RELATED ILLNESSES, SUCH AS STRESS-INDUCED DEPRESSION, ANXIETY, AND HEADACHE; ABDOMINAL BOWEL SYNDROME; INFLAMMATORY DISEASES; IMMUNE SUPPRESSION; ALZHEIMER'S DISEASE; GASTRONINTESTINAL DISEASES | PFIZER INC | 2001-04-17 | — | — | US | disclosed |
| EP-0674642-B1 | PYRAZOLOPYRIMIDINES AS CRF ANTAGONISTS | PFIZER (US) | 2000-08-23 | — | — | EP | disclosed |
| CN-1034175-C | pyrazolopyrimidines | PFIZER (US) | 1997-03-05 | — | — | CN | disclosed |
| EP-0674642-A1 | PYRAZOLOPYRIMIDINES AS CRF ANTAGONISTS | PFIZER INC. (US) | 1995-10-04 | — | — | EP | disclosed |
| CN-1094048-A | Pyrazolopyrimidines | PFIZER (US) | 1994-10-26 | — | — | CN | disclosed |
| WO-1994013677-A1 | PYRAZOLOPYRIMIDINES AS CRF ANTAGONISTS | PFIZER INC. (US) | 1994-06-23 | — | — | WO | disclosed |