SCHEMBL3701532

SCHEMBL3701532

CC(C)c1cc(C(C)C)cc(C(c2ccc(O)cc2)c2cc(C(C)C)cc(C(C)C)c2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.52
ESR2 Q92731 8/20 0.52
PDCD1 Q15116 1/20 0.52
CD274 Q9NZQ7 1/20 0.52
PTGS1 P23219 2/20 0.43
TRPA1 O75762 1/20 0.43
CACNA1C Q13936 1/20 0.43
ALDH1A1 P00352 1/20 0.42
GAA P10253 1/20 0.42
ALOX12 P18054 1/20 0.42
HTT P42858 1/20 0.42
HIF1A Q16665 1/20 0.42
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
PGR P06401 1/20 0.41
CHRM2 P08172 1/20 0.41
CYP3A4 P08684 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
AR P10275 1/20 0.41
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1448115 0.88 ESR1 (0.59) ESR1ESR2PDCD1CD274PTGS1
Hydroquinone SCHEMBL10526088 0.88 ESR1 (0.57) ESR1ESR2PDCD1CD274PTGS1
Hydroquinone SCHEMBL9580215 0.80 ESR1 (0.68) ESR1ESR2PDCD1CD274PTGS1
SCHEMBL28954 0.80 ESR1 (0.68) ESR1ESR2PDCD1CD274PTGS1
SCHEMBL216712 0.80 ESR1 (0.58) ESR1ESR2PDCD1CD274PTGS1
SCHEMBL40254 0.80 ESR1 (0.58) ESR1ESR2PDCD1CD274PTGS1
SCHEMBL31274990 0.80 ESR1 (0.58) ESR1ESR2PDCD1CD274PTGS1
SCHEMBL3694310 0.79 ALDH1A1 (0.43) PTGS1TRPA1CACNA1CALDH1A1GAA
SCHEMBL9808121 0.78 ESR1 (0.84) ESR1ESR2PDCD1CD274PTGS1
SCHEMBL3693258 0.78 ESR1 (0.43) ESR1ESR2PDCD1CD274PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741240-B2 Transition metal compounds for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-06-22 US claimed
EP-1753773-A1 TRANSITION METAL COMPOUNDS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION ExxonMobil Chemical Patents Inc. (US) 2007-02-21 EP claimed
WO-2005118605-A1 TRANSITION METAL COMPOUNDS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2005-12-15 WO claimed