SCHEMBL3693258

SCHEMBL3693258

CC(C)c1cc(C(c2ccc(O)cc2)c2cc(C(C)C)c(N)c(C(C)C)c2)cc(C(C)C)c1N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.43
ESR2 Q92731 3/20 0.43
PDCD1 Q15116 1/20 0.43
CD274 Q9NZQ7 1/20 0.43
GAA P10253 3/20 0.40
ALDH1A1 P00352 2/20 0.40
HIF1A Q16665 2/20 0.40
ALOX12 P18054 1/20 0.40
HTT P42858 1/20 0.40
TAAR1 Q96RJ0 5/20 0.37
SLC6A2 P23975 2/20 0.37
GABRA1 P14867 1/20 0.37
GABRB2 P47870 1/20 0.37
TDP1 Q9NUW8 2/20 0.35
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35
PGR P06401 1/20 0.35
CHRM2 P08172 1/20 0.35
CYP3A4 P08684 1/20 0.35
ADORA3 P0DMS8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3696192 0.86 ALDH1A1 (0.39) GAAALDH1A1HIF1AALOX12HTT
SCHEMBL3696531 0.81 GABRA1 (0.35) GAAALDH1A1HIF1AALOX12HTT
SCHEMBL28523547 0.81 ADRA2A (0.41) ALDH1A1HIF1ATAAR1SLC6A2LMNA
SCHEMBL3689051 0.81 ADRA2A (0.41) ALDH1A1HIF1ATAAR1SLC6A2LMNA
SCHEMBL28604268 0.81 GABRA1 (0.35) GAAALDH1A1HIF1AALOX12HTT
SCHEMBL25505374 0.79 ESR1 (0.45) ESR1ESR2PDCD1CD274GAA
SCHEMBL2202094 0.79 ESR1 (0.45) ESR1ESR2PDCD1CD274GAA
SCHEMBL3701532 0.78 ESR1 (0.52) ESR1ESR2PDCD1CD274GAA
SCHEMBL30782957 0.78 ADRA2A (0.38) ALDH1A1HIF1ATAAR1SLC6A2LMNA
SCHEMBL30577327 0.78 ADRA2A (0.38) ALDH1A1HIF1ATAAR1SLC6A2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741240-B2 Transition metal compounds for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-06-22 US disclosed
US-20080033125-A1 Transition Metal Compounds for Olefin Polymerization and Oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2008-02-07 US disclosed