⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3700799 | 0.80 | SORD (0.33) | — | |
| SCHEMBL1709814 | 0.80 | GPR6 (0.33) | — | |
| SCHEMBL3711697 | 0.77 | STK4 (0.36) | — | |
| SCHEMBL3706410 | 0.76 | HRH4 (0.35) | — | |
| SCHEMBL3703726 | 0.76 | OPRK1 (0.33) | — | |
| SCHEMBL3700685 | 0.74 | SYK (0.56) | — | |
| SCHEMBL3702492 | 0.72 | PTPN11 (0.36) | — | |
| SCHEMBL189922 | 0.70 | SMN1; SMN2 (0.49) | — | |
| SCHEMBL1709781 | 0.69 | NCF1 (0.43) | — | |
| SCHEMBL1709783 | 0.69 | HTR2C (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8551981-B2 | Furo[3,2-d]pyrimidine compounds | ABBVIE INC. (US) | 2013-10-08 | — | — | US | disclosed |
| US-20120122846-A1 | FURO[3,2-d]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2012-05-17 | — | — | US | disclosed |