Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362374 | 0.86 | TSHR (0.63) | TSHRALDH1A1THRB | |
| SCHEMBL2168154 | 0.81 | ALDH1A1 (0.41) | TSHRALDH1A1 | |
| SCHEMBL5027278 | 0.79 | TSHR (0.70) | TSHRALDH1A1THRB | |
| SCHEMBL4331907 | 0.79 | TSHR (0.76) | TSHRALDH1A1THRB | |
| SCHEMBL24562 | 0.78 | TSHR (1.00) | TSHRALDH1A1THRB | |
| SCHEMBL730198 | 0.78 | TSHR (0.68) | TSHRALDH1A1THRB | |
| SCHEMBL28562708 | 0.78 | TSHR (0.62) | TSHRALDH1A1THRB | |
| SCHEMBL1336820 | 0.77 | TSHR (0.73) | TSHRALDH1A1THRB | |
| SCHEMBL761374 | 0.77 | TSHR (0.73) | TSHRALDH1A1THRB | |
| SCHEMBL160208 | 0.77 | TSHR (0.73) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |