Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1984274 | 0.92 | PTGES (0.42) | PTGES | |
| SCHEMBL6124864 | 0.87 | PTGES (0.43) | PTGESABL1 | |
| SCHEMBL2683599 | 0.87 | PTGES (0.39) | PTGES | |
| SCHEMBL3703312 | 0.81 | PTGES (0.48) | PTGES | |
| SCHEMBL16318524 | 0.81 | PTGES (0.51) | PTGESABL1 | |
| SCHEMBL2683766 | 0.80 | PTGES (0.38) | PTGES | |
| SCHEMBL2683762 | 0.80 | PTGES (0.37) | PTGES | |
| SCHEMBL3701439 | 0.80 | PTGES (0.47) | PTGES | |
| SCHEMBL1975779 | 0.80 | MAPT (0.41) | PTGESABL1 | |
| SCHEMBL1970965 | 0.79 | PTGES (0.57) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040565-B2 | 1H-benzimidazole-5-carboxamides as anti-inflammatory agents | OREXO AB (SE) | 2015-05-26 | — | — | US | claimed |
| US-20120122930-A1 | 1H-Benzimidazole-5-Carboxamides As Anti-Inflammatory Agents | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-05-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122930-A1 | 1H-Benzimidazole-5-Carboxamides As Anti-Inflammatory Agents | MAPRE2, MAPRE1, MAP4 | PTGES 179/4885ABL1 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.