Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.44 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.44 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3712977 | 0.99 | MAPT (0.48) | MAPTL3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL3707936 | 0.84 | MAPT (0.51) | MAPTL3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL3806875 | 0.80 | MAPT (0.58) | MAPTL3MBTL3L3MBTL1MBTD1TP53BP1 | |
| Hydrochloric Acid SCHEMBL3708195 | 0.78 | MAPT (0.69) | MAPTL3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL3800379 | 0.76 | MAPT (0.53) | MAPTL3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL3703302 | 0.76 | OPRM1 (0.41) | L3MBTL3MBTD1 | |
| Hydrochloric Acid SCHEMBL3707110 | 0.75 | OPRM1 (0.41) | L3MBTL3MBTD1 | |
| Hydrochloric Acid SCHEMBL3715814 | 0.74 | MAPT (0.52) | MAPTL3MBTL3L3MBTL1MBTD1TP53BP1 | |
| Hydrochloric Acid SCHEMBL3716255 | 0.73 | L3MBTL3 (0.71) | MAPTL3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL13284116 | 0.72 | PARP1 (0.47) | L3MBTL3L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |