Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 15/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 11/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.34 |
| ▸ | WNT1 | P04628 | 5/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | CLK3 | P49761 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3702434 | 0.99 | DPP4 (0.34) | DPP4DPP8DPP9DPP7WNT1 | |
| SCHEMBL3703580 | 0.74 | POLB (0.42) | WNT1DYRK1A | |
| Hydrochloric Acid SCHEMBL3702431 | 0.73 | POLB (0.42) | WNT1DYRK1A | |
| SCHEMBL3703584 | 0.70 | DYRK1A (0.38) | DPP7WNT1DYRK1A | |
| SCHEMBL3698706 | 0.70 | MPO (0.44) | — | |
| Hydrochloric Acid SCHEMBL3702436 | 0.69 | DYRK1A (0.37) | DPP7WNT1DYRK1A | |
| SCHEMBL3697876 | 0.69 | ROCK1 (0.40) | — | |
| SCHEMBL13604787 | 0.69 | RAB9A (0.41) | WNT1DYRK1A | |
| SCHEMBL3694384 | 0.69 | ROCK2 (0.38) | — | |
| Hydrochloric Acid SCHEMBL3695123 | 0.68 | ROCK2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1851199-B1 | SUBSTITUTED BIS ARYL AND HETEROARYL COMPOUNDS AS SELECTIVE 5HT2A ANTAGONISTS | AVENTIS PHARMA INC (US) | 2012-05-16 | — | — | EP | claimed |