Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 14/20 | 0.44 |
| ▸ | THRA | P10827 | 12/20 | 0.44 |
| ▸ | STAT3 | P40763 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3704624 | 0.89 | THRB (0.48) | THRBTHRASTAT3 | |
| SCHEMBL3219975 | 0.86 | THRB (0.40) | THRBTHRAHSP90AA1HSP90AB1 | |
| SCHEMBL3713193 | 0.83 | THRA (0.51) | THRBTHRA | |
| SCHEMBL3708498 | 0.82 | THRA (0.61) | THRBTHRA | |
| SCHEMBL3707632 | 0.82 | THRA (0.40) | THRBTHRA | |
| SCHEMBL3778662 | 0.82 | THRB (0.63) | THRBTHRA | |
| SCHEMBL3713941 | 0.81 | THRB (0.50) | THRBTHRASTAT3HSP90AA1 | |
| SCHEMBL3705942 | 0.80 | THRB (0.45) | THRBTHRASTAT3 | |
| SCHEMBL3711117 | 0.80 | TSHR (0.43) | THRB | |
| SCHEMBL3807063 | 0.78 | THRB (0.58) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | disclosed |