SCHEMBL3704074

SCHEMBL3704074

Cc1cc(C)cc(C(c2ccc(Br)cc2)c2cc(C)cc(C)c2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
RAPGEF4 Q8WZA2 1/20 0.39
CYP1A2 P05177 2/20 0.36
CYP2A6 P11509 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPK1 P28482 2/20 0.35
ALOX15 P16050 1/20 0.35
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
HTR2A P28223 1/20 0.33
CYP19A1 P11511 1/20 0.33
ALOX5 P09917 1/20 0.32
IGF1R P08069 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
PYCR1 P32322 1/20 0.32
CYP3A4 P08684 1/20 0.31
CYP2C19 P33261 1/20 0.31
HTT P42858 1/20 0.31
XDH P47989 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27251934 0.83 ALDH1A1 (0.68) ALDH1A1CYP1A2CYP2A6MEN1KMT2A
SCHEMBL4950926 0.80 ALDH1A1 (0.44) ALDH1A1RAPGEF4MAPK1CYP3A4
SCHEMBL1989430 0.80 CYP2A6 (0.57) ALDH1A1CYP1A2CYP2A6MAPK1ALOX15
SCHEMBL27955728 0.79 ACHE (0.48) ALDH1A1MEN1KMT2AMAPK1ALOX15
SCHEMBL3697491 0.79 ACHE (0.48) ALDH1A1MEN1KMT2AMAPK1ALOX15
SCHEMBL3696722 0.77 ESR1 (0.46) ALDH1A1RAPGEF4CYP1A2MEN1KMT2A
SCHEMBL3699760 0.77 ACHE (0.31) ALDH1A1
SCHEMBL3696526 0.77 CYP19A1 (0.50) CYP2A6MAPK1CYP19A1
SCHEMBL3690665 0.77 ACHE (0.46) ALDH1A1MEN1KMT2ACYP19A1
SCHEMBL3688225 0.77 POLB (0.37) ALDH1A1CYP1A2CYP2A6MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741240-B2 Transition metal compounds for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-06-22 US claimed
EP-1753773-A1 TRANSITION METAL COMPOUNDS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION ExxonMobil Chemical Patents Inc. (US) 2007-02-21 EP claimed
WO-2005118605-A1 TRANSITION METAL COMPOUNDS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS, INC. (US) 2005-12-15 WO claimed