Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 17/20 | 0.46 |
| ▸ | THRA | P10827 | 16/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3710141 | 0.92 | THRB (0.51) | THRBTHRASTAT3 | |
| SCHEMBL3710521 | 0.89 | THRB (0.46) | THRBTHRASTAT3 | |
| SCHEMBL3705055 | 0.86 | STAT3 (0.48) | THRBTHRASTAT3 | |
| SCHEMBL3718169 | 0.82 | THRB (0.43) | THRBTHRA | |
| SCHEMBL3704624 | 0.82 | THRB (0.48) | THRBTHRASTAT3 | |
| SCHEMBL3712021 | 0.80 | THRB (0.42) | THRBTHRASTAT3 | |
| SCHEMBL3709651 | 0.80 | THRB (0.52) | THRBTHRASTAT3 | |
| SCHEMBL3704933 | 0.80 | NR3C1 (0.38) | THRBTHRA | |
| SCHEMBL3708122 | 0.80 | THRB (0.45) | THRBTHRASTAT3 | |
| SCHEMBL3705716 | 0.79 | THRB (0.46) | THRBTHRASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | claimed |
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | disclosed |