Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 12/20 | 0.47 |
| ▸ | THRA | P10827 | 11/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3710521 | 0.92 | THRB (0.46) | STAT3THRBTHRA | |
| SCHEMBL3710141 | 0.91 | THRB (0.51) | STAT3THRBTHRAPTGES | |
| SCHEMBL3705791 | 0.90 | STAT3 (0.44) | STAT3THRBTHRAPTGES | |
| SCHEMBL3704309 | 0.86 | THRB (0.46) | STAT3THRBTHRA | |
| SCHEMBL3226105 | 0.85 | THRB (0.41) | STAT3THRBTHRAPTGES | |
| SCHEMBL3225769 | 0.85 | THRB (0.40) | STAT3THRBTHRAPTGES | |
| SCHEMBL3704624 | 0.83 | THRB (0.48) | STAT3THRBTHRA | |
| SCHEMBL3705929 | 0.83 | THRB (0.43) | STAT3THRBTHRA | |
| SCHEMBL3709651 | 0.81 | THRB (0.52) | STAT3THRBTHRA | |
| SCHEMBL3708122 | 0.81 | THRB (0.45) | STAT3THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | claimed |
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | disclosed |