Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | OGA | O60502 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31669101 | 0.84 | SLC6A3 (0.55) | PTGS1OGASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL22206745 | 0.83 | SLC6A3 (0.56) | PTGS1OGASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL22206766 | 0.83 | SLC6A3 (0.56) | PTGS1OGASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL29585835 | 0.83 | SLC6A3 (0.56) | PTGS1OGASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL29585404 | 0.83 | SLC6A3 (0.56) | PTGS1OGASLC6A2SLC6A3SLC6A4 | |
| SCHEMBL6206243 | 0.75 | HSD11B1 (0.57) | OGACYP2D6HSD11B1ALDH1A1 | |
| SCHEMBL6306254 | 0.75 | HSD11B1 (0.57) | OGACYP2D6HSD11B1ALDH1A1 | |
| SCHEMBL4601165 | 0.75 | CYP2D6 (0.70) | OPRM1CYP2D6HSD11B1ALDH1A1 | |
| SCHEMBL13283877 | 0.75 | HSD11B1 (0.52) | SLC6A2SLC6A3SLC6A4OPRM1CYP2D6 | |
| SCHEMBL1586528 | 0.75 | CYP2D6 (0.70) | OPRM1CYP2D6HSD11B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |