Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | OGA | O60502 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29585404 | 1.00 | SLC6A3 (0.56) | SLC6A3SLC6A2SLC6A4PTGS1OGA | |
| SCHEMBL22206745 | 1.00 | SLC6A3 (0.56) | SLC6A3SLC6A2SLC6A4PTGS1OGA | |
| SCHEMBL22206766 | 1.00 | SLC6A3 (0.56) | SLC6A3SLC6A2SLC6A4PTGS1OGA | |
| SCHEMBL31669101 | 0.98 | SLC6A3 (0.55) | SLC6A3SLC6A2SLC6A4PTGS1OGA | |
| SCHEMBL6447344 | 0.86 | SLC6A3 (0.48) | SLC6A3SLC6A2SLC6A4PTGS1SMN1; SMN2 | |
| SCHEMBL5554008 | 0.86 | SLC6A3 (0.48) | SLC6A3SLC6A2SLC6A4PTGS1SMN1; SMN2 | |
| SCHEMBL3704355 | 0.83 | PTGS1 (0.50) | SLC6A3SLC6A2SLC6A4PTGS1OGA | |
| SCHEMBL22206767 | 0.79 | CHRM2 (0.57) | SLC6A3SLC6A2SLC6A4SMN1; SMN2MEN1 | |
| SCHEMBL22206739 | 0.79 | CHRM2 (0.57) | SLC6A3SLC6A2SLC6A4SMN1; SMN2MEN1 | |
| SCHEMBL7312748 | 0.78 | SLC6A2 (0.68) | SLC6A3SLC6A2SLC6A4SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158372-A1 | BISAMIDE SARCOMERE ACTIVATING COMPOUNDS AND USES THEREOF | AMGEN INC. | 2024-05-16 | — | — | US | disclosed |
| US-11780826-B2 | Bisamide sarcomere activating compounds and uses thereof | AMGEN INC. (US) | 2023-10-10 | — | — | US | disclosed |
| US-20220281850-A1 | BISAMIDE SARCOMERE ACTIVATING COMPOUNDS AND USES THEREOF | AMGEN INC. | 2022-09-08 | — | — | US | disclosed |
| US-11299479-B1 | Bisamide sarcomere activating compounds and uses thereof | CYTOKINETICS, INC. (US) | 2022-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11780826-B2 | Bisamide sarcomere activating compounds and uses thereof | TNNI3, TNNT2, TNNC1 | SLC6A3 4306/4885SLC6A2 1343/4885SLC6A4 2425/4885 |
| US-20240158372-A1 | BISAMIDE SARCOMERE ACTIVATING COMPOUNDS AND USES THEREOF | TNNI3, TNNT2, TNNC1 | SLC6A3 4306/4885SLC6A2 1343/4885SLC6A4 2425/4885 |
| US-20220281850-A1 | BISAMIDE SARCOMERE ACTIVATING COMPOUNDS AND USES THEREOF | TNNI3, TNNT2, TNNC1 | SLC6A3 4306/4885SLC6A2 1343/4885SLC6A4 2425/4885 |
| US-11299479-B1 | Bisamide sarcomere activating compounds and uses thereof | TNNI3, TNNT2, TNNC1 | SLC6A3 4306/4885SLC6A2 1343/4885SLC6A4 2425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.